Transcript: lnc-CRYBA4-52:28

Basic information

LNCipedia transcript ID: lnc-CRYBA4-52:28 
HGNC Gene Symbol: lnc-CRYBA4-52    
HGNC Full Gene Name: myocardial infarction associated transcript
Ensembl Gene ID: ENSG00000225783
Ensembl Transcript ID: ENST00000452429
Location (hg38): chr22:26657284-26666023
Strand: +
Class: intergenic
Sequence Ontology term: lincRNA
Transcript size: 894 bp
Exons: 4
Sources: Biogazelle lncRNA chip; Ensembl release 64 - Sep 2011; Gencode v13; Ensembl release 68 - Jul 2012; NONCODE v4; Ensembl release 75 - Feb 2014; Ensembl release 83 - Dec 2015; Ensembl release 87 - Dec 2016; Ensembl release 90 - Aug 2017; Ensembl release 92 - Apr 2018
Alternative transcript names: ENST00000452429; ENST00000452429.1; MIAT-016; OTTHUMT00000320811.1; NONHSAT084518; ENST00000452429.5
Alternative gene names: ENSG00000225783; MIAT; ENSG00000225783.2; OTTHUMG00000150985.2; ENSG00000225783.6; ; ENSG00000225783.7


RNA sequence:

Structure:

Protein coding potential

Metric Raw result Interpretation
PRIDE reprocessing 2.0 0 non-coding 
Lee translation initiation sites 0 non-coding 
PhyloCSF score -36.3893 non-coding 
CPAT coding probability 9.54% non-coding 
Bazzini small ORFs 0 non-coding 

In stringent set: yes

Locus conservation

Locus conservation?
lnc-CRYBA4-52:28 no no no no

Available literature

  1. Briese (2016), Whole transcriptome profiling reveals the RNA content of motor axons., Nucleic Acids Res.
  2. Ichigozaki (2016), Serum long non-coding RNA, snoRNA host gene 5 level as a new tumor marker of malignant melanoma., Exp. Dermatol.
  3. Liao (2016), LncRNA MIAT: Myocardial infarction associated and more., Gene
  4. Rosa (2016), Long Noncoding RNA Regulation of Pluripotency., Stem Cells Int
  5. Cabili (2015), Localization and abundance analysis of human lncRNAs at single-cell and single-molecule resolution., Genome Biol.
  6. Fiedler (2015), Development of Long Noncoding RNA-Based Strategies to Modulate Tissue Vascularization., J. Am. Coll. Cardiol.
  7. Li (2015), Construction and analysis of lncRNA-lncRNA synergistic networks to reveal clinically relevant lncRNAs in cancer., Oncotarget
  8. Rao (2015), Genetic variants in long non-coding RNA MIAT contribute to risk of paranoid schizophrenia in a Chinese Han population., Schizophr. Res.
  9. Wang (2015), Identification of lncRNA-associated competing triplets reveals global patterns and prognostic markers for cancer., Nucleic Acids Res.
  10. Yan (2015), lncRNA-MIAT regulates microvascular dysfunction by functioning as a competing endogenous RNA., Circ. Res.
  11. Zhou (2015), Long non-coding MIAT mediates high glucose-induced renal tubular epithelial injury., Biochem. Biophys. Res. Commun.
  12. Barry (2014), The long non-coding RNA Gomafu is acutely regulated in response to neuronal activation and involved in schizophrenia-associated alternative splicing., Mol. Psychiatry
  13. Roberts (2014), The role of long non-coding RNAs in neurodevelopment, brain function and neurological disease., Philos. Trans. R. Soc. Lond., B, Biol. Sci.
  14. Skroblin (2014), "Going long": long non-coding RNAs as biomarkers., Circ. Res.
  15. Vausort (2014), Long noncoding RNAs in patients with acute myocardial infarction., Circ. Res.
  16. Abdelmohsen (2013), Senescence-associated lncRNAs: senescence-associated long noncoding RNAs., Aging Cell
  17. Hangauer (2013), Pervasive transcription of the human genome produces thousands of previously unidentified long intergenic noncoding RNAs., PLoS Genet.
  18. Zhang (2013), A long non-coding RNA signature in glioblastoma multiforme predicts survival., Neurobiol. Dis.
  19. Bánfai (2012), Long noncoding RNAs are rarely translated in two human cell lines., Genome Res.
  20. Derrien (2012), The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression., Genome Res.
  21. Ip (2012), Long non-coding RNAs in nuclear bodies., Dev. Growth Differ.
  22. Lin (2011), RNA-Seq of human neurons derived from iPS cells reveals candidate long non-coding RNAs involved in neurogenesis and neuropsychiatric disorders., PLoS ONE
  23. Tollervey (2011), Characterizing the RNA targets and position-dependent splicing regulation by TDP-43., Nat. Neurosci.
  24. Sone (2007), The mRNA-like noncoding RNA Gomafu constitutes a novel nuclear domain in a subset of neurons., J. Cell. Sci.
  25. Ishii (2006), Identification of a novel non-coding RNA, MIAT, that confers risk of myocardial infarction., J. Hum. Genet.


LNCipedia transcript ID history

LNCipedia version LNCipedia transcript ID
1.3 lnc-CRYBA4-1:13
3.1 lnc-CRYBA4-1:13
4.0 lnc-CRYBA4-1:13
4.1 LINC01422:44
5.0 LINC01422:44
5.1 lnc-CABIN1-52:28
5.2 lnc-CRYBA4-52:28