Long non-coding RNA (lncRNA) constitutes a large and diverse class of non-coding RNA genes. While several lncRNAs have been functionally annotated, the majority remains to be characterized. Different high-throughput methods to identify new lncRNAs (including RNA sequencing and annotation of chromatin-state maps) have been applied in various studies resulting in multiple unrelated lncRNA datasets.
Lncipedia.org is an integrated database of 118,777 human annotated lncRNA transcripts obtained from different sources. In addition to basic transcript information and structure, several statistics are calculated for each entry in the database, such as secondary structure information, protein coding potential and microRNA binding sites.
The database is publicly available and allows users to query and download lncRNA sequences and structures based on different search criteria. The database may serve as a source of information on individual lncRNAs or as a starting point for large-scale studies.
The lncRNA research community is encouraged to submit data to LNCipedia:
Please use the following citations when referring to LNCipedia:
An update on LNCipedia: a database for annotated human lncRNA sequences
Pieter-Jan Volders; Kenneth Verheggen; Gerben Menschaert; Klaas Vandepoele; Lennart Martens; Jo Vandesompele and Pieter Mestdagh
Nucleic Acids Research 2014; doi: 10.1093/nar/gku1060 [citations in Google Scholar]
LNCipedia: a database for annotated human lncRNA transcript sequences and structures
Pieter-Jan Volders; Kenny Helsens; Xiaowei Wang; Bjorn Menten; Lennart Martens; Kris Gevaert; Jo Vandesompele; Pieter Mestdagh
Nucleic Acids Research 2012; doi: 10.1093/nar/gks915 [citations in Google Scholar]