Transcript: TUG1:13
Basic information
LNCipedia transcript ID: TUG1:13
LNCipedia gene ID: TUG1
Location (hg38): chr22:30969712-30979396
Strand: +
Class: intergenic
Sequence Ontology term: lincRNA
Transcript size: 7167 bp
Exons: 4
Sources: Sun and Gadad et al., 2015
Alternative transcript names: LncRNA916:3
Alternative gene names: FLJ20618; NCRNA00080; LINC00080
RNA sequence:
Structure:
Protein coding potential
| Metric |
Raw result |
Interpretation |
| PRIDE reprocessing 2.0 |
0 |
non-coding |
| Lee translation initiation sites |
|
non-coding |
| PhyloCSF score |
-124.9389 |
non-coding |
| CPAT coding probability |
1.63% |
non-coding |
| Bazzini small ORFs |
0 |
non-coding |
In stringent set:
yes
Locus conservation
| Locus conservation? |
 |
 |
 |
 |
| TUG1:13 |
no
|
no
|
no
|
no
|
Available literature
-
Wang
(2017),
Long non-coding RNA TUG1 promotes migration and invasion by acting as a ceRNA of miR-335-5p in osteosarcoma cells.,
Cancer Sci.
-
Lennox
(2016),
Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides.,
Nucleic Acids Res.
-
Ma
(2016),
Upregulation of long non-coding RNA TUG1 correlates with poor prognosis and disease status in osteosarcoma.,
Tumour Biol.
-
Cai
(2015),
The long noncoding RNA TUG1 regulates blood-tumor barrier permeability by targeting miR-144.,
Oncotarget
-
Hu
(2015),
Protein arginine methyltransferase CARM1 attenuates the paraspeckle-mediated nuclear retention of mRNAs containing IRAlus.,
Genes Dev.
-
Huang
(2015),
Long non-coding RNA TUG1 is up-regulated in hepatocellular carcinoma and promotes cell growth and apoptosis by epigenetically silencing of KLF2.,
Mol. Cancer
-
Imam
(2015),
The lncRNA NRON modulates HIV-1 replication in a NFAT-dependent manner and is differentially regulated by early and late viral proteins.,
Sci Rep
-
Liu
(2015),
Altered expression of long non-coding RNAs during genotoxic stress-induced cell death in human glioma cells.,
J. Neurooncol.
-
Pastori
(2015),
The Bromodomain protein BRD4 controls HOTAIR, a long noncoding RNA essential for glioblastoma proliferation.,
Proc. Natl. Acad. Sci. U.S.A.
-
Sugihara
(2015),
Noncoding RNA Expression Aberration Is Associated with Cancer Progression and Is a Potential Biomarker in Esophageal Squamous Cell Carcinoma.,
Int J Mol Sci
-
Tan
(2015),
Double-negative feedback loop between long non-coding RNA TUG1 and miR-145 promotes epithelial to mesenchymal transition and radioresistance in human bladder cancer cells.,
FEBS Lett.
-
Wang
(2015),
Identification of lncRNA-associated competing triplets reveals global patterns and prognostic markers for cancer.,
Nucleic Acids Res.
-
Wang
(2015),
The mitotic regulator Hec1 is a critical modulator of prostate cancer through the long non-coding RNA BX647187 in vitro.,
Biosci. Rep.
-
Xu
(2015),
Upregulation of the long noncoding RNA TUG1 promotes proliferation and migration of esophageal squamous cell carcinoma.,
Tumour Biol.
-
Yin
(2015),
Downregulation of lncRNA TUG1 affects apoptosis and insulin secretion in mouse pancreatic β cells.,
Cell. Physiol. Biochem.
-
Gezer
(2014),
Long non-coding RNAs with low expression levels in cells are enriched in secreted exosomes.,
Cell Biol. Int.
-
Isin
(2014),
Investigation of circulating lncRNAs in B-cell neoplasms.,
Clin. Chim. Acta
-
Li
(2014),
Discovery of Protein-lncRNA Interactions by Integrating Large-Scale CLIP-Seq and RNA-Seq Datasets.,
Front Bioeng Biotechnol
-
Michalik
(2014),
Long noncoding RNA MALAT1 regulates endothelial cell function and vessel growth.,
Circ. Res.
-
Puvvula
(2014),
Long noncoding RNA PANDA and scaffold-attachment-factor SAFA control senescence entry and exit.,
Nat Commun
-
Roberts
(2014),
The role of long non-coding RNAs in neurodevelopment, brain function and neurological disease.,
Philos. Trans. R. Soc. Lond., B, Biol. Sci.
-
Wan
(2014),
Noncoding RNAs in DNA repair and genome integrity.,
Antioxid. Redox Signal.
-
Zhang
(2014),
P53-regulated long non-coding RNA TUG1 affects cell proliferation in human non-small cell lung cancer, partly through epigenetically regulating HOXB7 expression.,
Cell Death Dis
-
van Heesch
(2014),
Extensive localization of long noncoding RNAs to the cytosol and mono- and polyribosomal complexes.,
Genome Biol.
-
Cao
(2013),
Analysis of long non-coding RNA expression profiles in gastric cancer.,
World J. Gastroenterol.
-
Chen
(2013),
Novel human lncRNA-disease association inference based on lncRNA expression profiles.,
Bioinformatics
-
Han
(2013),
Long intergenic non-coding RNA TUG1 is overexpressed in urothelial carcinoma of the bladder.,
J Surg Oncol
-
Kapusta
(2013),
Transposable elements are major contributors to the origin, diversification, and regulation of vertebrate long noncoding RNAs.,
PLoS Genet.
-
Liu
(2013),
WITHDRAWN: Down-regulation of long non-coding RNA TUG1 suppresses melanoma cell proliferation and induces apoptosis via up-regulating microRNA-9.,
Biochem. Biophys. Res. Commun.
-
Liu
(2013),
Probing N6-methyladenosine RNA modification status at single nucleotide resolution in mRNA and long noncoding RNA.,
RNA
-
Sauvageau
(2013),
Multiple knockout mouse models reveal lincRNAs are required for life and brain development.,
Elife
-
Wan
(2013),
Long non-coding RNA ANRIL (CDKN2B-AS) is induced by the ATM-E2F1 signaling pathway.,
Cell. Signal.
-
Zhang
(2013),
Down-regulation of long non-coding RNA TUG1 inhibits osteosarcoma cell proliferation and promotes apoptosis.,
Asian Pac. J. Cancer Prev.
-
Özgür
(2013),
Differential expression of long non-coding RNAs during genotoxic stress-induced apoptosis in HeLa and MCF-7 cells.,
Clin. Exp. Med.
-
Clark
(2012),
Genome-wide analysis of long noncoding RNA stability.,
Genome Res.
-
Jalali
(2012),
Integrative transcriptome analysis suggest processing of a subset of long non-coding RNAs to small RNAs.,
Biol. Direct
-
Johnson
(2012),
Long non-coding RNAs in Huntington's disease neurodegeneration.,
Neurobiol. Dis.
-
Kelley
(2012),
Transposable elements reveal a stem cell-specific class of long noncoding RNAs.,
Genome Biol.
-
Tani
(2012),
Genome-wide determination of RNA stability reveals hundreds of short-lived noncoding transcripts in mammals.,
Genome Res.
-
Friedel
(2009),
Conserved principles of mammalian transcriptional regulation revealed by RNA half-life.,
Nucleic Acids Res.
-
Guttman
(2009),
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals.,
Nature
-
Khalil
(2009),
Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression.,
Proc. Natl. Acad. Sci. U.S.A.
-
Young
(2005),
The noncoding RNA taurine upregulated gene 1 is required for differentiation of the murine retina.,
Curr. Biol.
LNCipedia transcript ID history
| LNCipedia version |
LNCipedia transcript ID |
| 4.0 |
TUG1:13 |
| 4.1 |
TUG1:13 |
| 5.0 |
TUG1:13 |
| 5.1 |
TUG1:13 |
| 5.2 |
TUG1:13 |