Transcript: lnc-FAM84B-15:112

Basic information

LNCipedia transcript ID: lnc-FAM84B-15:112 
HGNC Gene Symbol: lnc-FAM84B-15    
HGNC Full Gene Name: cancer susceptibility 8
Ensembl Gene ID: ENSG00000246228
Ensembl Transcript ID: ENST00000523825
Location (hg38): chr8:127289818-127421374
Strand: -
Class: antisense
Sequence Ontology term: antisense_lncRNA
Transcript size: 789 bp
Exons: 2
Sources: Biogazelle lncRNA chip; Ensembl release 64 - Sep 2011; Gencode v13; Ensembl release 68 - Jul 2012; NONCODE v4; Ensembl release 75 - Feb 2014; Ensembl release 83 - Dec 2015; Ensembl release 87 - Dec 2016; Ensembl release 90 - Aug 2017; Ensembl release 92 - Apr 2018
Alternative transcript names: ENST00000523825; ENST00000523825.1; RP11-382A18.1-001; OTTHUMT00000381644.1; NONHSAT129030
Alternative gene names: ENSG00000246228; RP11-382A18.1; ENSG00000246228.2; OTTHUMG00000165066.1; CASC8; ENSG00000246228.6


RNA sequence:

Structure:

Protein coding potential

Metric Raw result Interpretation
PRIDE reprocessing 2.0 0 non-coding 
Lee translation initiation sites 0 non-coding 
PhyloCSF score -35.1301 non-coding 
CPAT coding probability 1.74% non-coding 
Bazzini small ORFs 0 non-coding 

In stringent set: yes

Locus conservation

Locus conservation?
lnc-FAM84B-15:112 no no no no

Available literature

  1. Li (2016), Cancer RNA-Seq Nexus: a database of phenotype-specific transcriptome profiling in cancer cells., Nucleic Acids Res.
  2. Xie (2016), Long non-coding RNAs in colorectal cancer., Oncotarget
  3. Al-Tassan (2015), A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer., Sci Rep
  4. Cabanski (2015), Pan-cancer transcriptome analysis reveals long noncoding RNAs with conserved function., RNA Biol
  5. Deng (2015), Long noncoding RNA CCAT1 promotes hepatocellular carcinoma progression by functioning as let-7 sponge., J. Exp. Clin. Cancer Res.
  6. Hu (2015), Downregulation of NUF2 inhibits tumor growth and induces apoptosis by regulating lncRNA AF339813., Int J Clin Exp Pathol
  7. Kim (2015), MYC-repressed long noncoding RNAs antagonize MYC-induced cell proliferation and cell cycle progression., Oncotarget
  8. Ma (2015), Genetic variant in 8q24 is associated with prognosis for gastric cancer in a Chinese population., J. Gastroenterol. Hepatol.
  9. Ma (2015), Long non-coding RNA CCAT1 promotes gallbladder cancer development via negative modulation of miRNA-218-5p., Cell Death Dis
  10. Mizrahi (2015), Colon Cancer Associated Transcript-1 (CCAT1) Expression in Adenocarcinoma of the Stomach., J Cancer
  11. Ruan (2015), Long non-coding RNA expression profile in atrial fibrillation., Int J Clin Exp Pathol
  12. Ye (2015), Expression of lncRNA-CCAT1, E-cadherin and N-cadherin in colorectal cancer and its clinical significance., Int J Clin Exp Med
  13. Zhai (2015), Long noncoding RNA MALAT1 as a putative biomarker of lymph node metastasis: a meta-analysis., Int J Clin Exp Med
  14. Zhang (2015), Overexpression of long non-coding RNA CCAT1 is a novel biomarker of poor prognosis in patients with breast cancer., Int J Clin Exp Pathol
  15. Zhou (2015), Identification of the long non-coding RNA H19 in plasma as a novel biomarker for diagnosis of gastric cancer., Sci Rep
  16. Zhu (2015), CCAT1 promotes hepatocellular carcinoma cell proliferation and invasion., Int J Clin Exp Pathol
  17. Dryden (2014), Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C., Genome Res.
  18. He (2014), C-Myc-activated long noncoding RNA CCAT1 promotes colon cancer cell proliferation and invasion., Tumour Biol.
  19. Kam (2014), Detection of a long non-coding RNA (CCAT1) in living cells and human adenocarcinoma of colon tissues using FIT-PNA molecular beacons., Cancer Lett.
  20. Kim (2014), Long-range interaction and correlation between MYC enhancer and oncogenic long noncoding RNA CARLo-5., Proc. Natl. Acad. Sci. U.S.A.
  21. Li (2014), Non-coding RNAs and gastric cancer., World J. Gastroenterol.
  22. Xiang (2014), Human colorectal cancer-specific CCAT1-L lncRNA regulates long-range chromatin interactions at the MYC locus., Cell Res.
  23. Younger (2014), 'Lnc'-ing enhancers to MYC regulation., Cell Res.
  24. Alaiyan (2013), Differential expression of colon cancer associated transcript1 (CCAT1) along the colonic adenoma-carcinoma sequence., BMC Cancer
  25. Liu (2013), Identification of differentially expressed long non-coding RNAs in human ovarian cancer cells with different metastatic potentials., Cancer Biol Med
  26. Yang (2013), Long noncoding RNA CCAT1, which could be activated by c-Myc, promotes the progression of gastric carcinoma., J. Cancer Res. Clin. Oncol.
  27. Jin (2011), Human polymorphisms at long non-coding RNAs (lncRNAs) and association with prostate cancer risk., Carcinogenesis


LNCipedia transcript ID history

LNCipedia version LNCipedia transcript ID
1.3 lnc-TMEM75-3:3
3.1 lnc-TMEM75-3:3
4.0 lnc-TMEM75-3:3
4.1 lnc-TMEM75-3:3
5.0 lnc-TMEM75-3:3
5.1 lnc-FAM84B-15:4
5.2 lnc-FAM84B-15:112