Transcript: AIRN:2

Basic information

LNCipedia transcript ID: AIRN:2 
HGNC Gene Symbol: AIRN    
HGNC Full Gene Name: antisense of IGF2R non-protein coding RNA
Ensembl Gene ID: ENSG00000268257
Ensembl Transcript ID: ENST00000601203
RefSeq ID: NR_047514
Location (hg38): chr6:160003291-160007664
Strand: -
Class: antisense
Sequence Ontology term: antisense_lncRNA
Transcript size: 4374 bp
Exons: 1
Sources: NONCODE v4; Ensembl release 75 - Feb 2014; Refseq - Dec 2014; Ensembl release 83 - Dec 2015; Ensembl release 87 - Dec 2016; Ensembl release 90 - Aug 2017; Ensembl release 92 - Apr 2018; Refseq - NCBI Annotation Release 106
Alternative transcript names: NONHSAT115888; NR_047514; ENST00000601203.1; NR_047514.1
Alternative gene names: ENSG00000268257.2; AIRN; AIR; NCRNA00088; IGF2RAS; IGF2R-AS1


RNA sequence:

Structure:

Protein coding potential

Metric Raw result Interpretation
PRIDE reprocessing 2.0 0 non-coding 
Lee translation initiation sites 0 non-coding 
PhyloCSF score 70.2257 coding 
CPAT coding probability 6.23% non-coding 
Bazzini small ORFs 0 non-coding 

In stringent set: no

Locus conservation

Locus conservation?
AIRN:2 yes no no no

Available literature

  1. Kanduri (2016), Long noncoding RNAs: Lessons from genomic imprinting., Biochim. Biophys. Acta
  2. He (2015), LongTarget: a tool to predict lncRNA DNA-binding motifs and binding sites via Hoogsteen base-pairing analysis., Bioinformatics
  3. Smolle (2015), Long Non-Coding RNAs in Endometrial Carcinoma., Int J Mol Sci
  4. Roberts (2014), The role of long non-coding RNAs in neurodevelopment, brain function and neurological disease., Philos. Trans. R. Soc. Lond., B, Biol. Sci.
  5. Sun (2014), A novel antisense long noncoding RNA within the IGF1R gene locus is imprinted in hematopoietic malignancies., Nucleic Acids Res.
  6. Beato (2013), A new role for an old player: steroid receptor RNA Activator (SRA) represses hormone inducible genes., Transcription
  7. Kobayashi (2013), Epigenetic and transcriptional features of the novel human imprinted lncRNA GPR1AS suggest it is a functional ortholog to mouse Zdbf2linc., Epigenetics
  8. Niemczyk (2013), Imprinted chromatin around DIRAS3 regulates alternative splicing of GNG12-AS1, a long noncoding RNA., Am. J. Hum. Genet.
  9. Papait (2013), Long noncoding RNA: a new player of heart failure?, J Cardiovasc Transl Res
  10. Santoro (2013), Silencing by the imprinted Airn macro lncRNA: transcription is the answer., Cell Cycle
  11. Latos (2012), Airn transcriptional overlap, but not its lncRNA products, induces imprinted Igf2r silencing., Science
  12. Tilgner (2012), Deep sequencing of subcellular RNA fractions shows splicing to be predominantly co-transcriptional in the human genome but inefficient for lncRNAs., Genome Res.
  13. Troy (2012), Genetic "lnc"-age of noncoding RNAs to human disease., J. Clin. Invest.
  14. Saxena (2011), Long non-coding RNA modifies chromatin: epigenetic silencing by long non-coding RNAs., Bioessays
  15. Stricker (2008), Silencing and transcriptional properties of the imprinted Airn ncRNA are independent of the endogenous promoter., EMBO J.
  16. Yotova (2008), Identification of the human homolog of the imprinted mouse Air non-coding RNA., Genomics


LNCipedia transcript ID history

LNCipedia version LNCipedia transcript ID
3.1 lnc-SLC22A2-4:1
4.0 AIRN:2
4.1 AIRN:2
5.0 AIRN:2
5.1 AIRN:2
5.2 AIRN:2