Transcript: ATXN8OS:6
Basic information
LNCipedia transcript ID: ATXN8OS:6
HGNC Gene Symbol: ATXN8OS
HGNC Full Gene Name:
ATXN8 opposite strand lncRNA
Ensembl Gene ID:
ENSG00000230223
Ensembl Transcript ID:
ENST00000424524
Location (hg38): chr13:70107912-70131546
Strand: +
Class: antisense
Sequence Ontology term: antisense_lncRNA
Transcript size: 1236 bp
Exons: 4
Sources: Gencode v13; Ensembl release 68 - Jul 2012; NONCODE v4; Ensembl release 75 - Feb 2014; Ensembl release 83 - Dec 2015; Ensembl release 87 - Dec 2016; Ensembl release 90 - Aug 2017; Ensembl release 92 - Apr 2018
Alternative transcript names: ENST00000424524.1; ATXN8OS-001; OTTHUMT00000045232.1; NONHSAT034253
Alternative gene names: ENSG00000230223.1; ATXN8OS; OTTHUMG00000017057.1; ENSG00000230223.2; ENSG00000230223.6; NCRNA00003
RNA sequence:
Structure:
Protein coding potential
In stringent set: yes
Locus conservation
Available literature
- Imam (2015), The lncRNA NRON modulates HIV-1 replication in a NFAT-dependent manner and is differentially regulated by early and late viral proteins., Sci Rep
- Quek (2015), lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs., Nucleic Acids Res.
- Qureshi (2012), Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease., Nat. Rev. Neurosci.
- Daughters (2009), RNA gain-of-function in spinocerebellar ataxia type 8., PLoS Genet.
- Chen (2008), SCA8 mRNA expression suggests an antisense regulation of KLHL1 and correlates to SCA8 pathology., Brain Res.
- Moseley (2006), Bidirectional expression of CUG and CAG expansion transcripts and intranuclear polyglutamine inclusions in spinocerebellar ataxia type 8., Nat. Genet.
- Mutsuddi (2004), The spinocerebellar ataxia 8 noncoding RNA causes neurodegeneration and associates with staufen in Drosophila., Curr. Biol.
- Benzow (2002), The KLHL1-antisense transcript ( KLHL1AS) is evolutionarily conserved., Mamm. Genome
- Nemes (2000), The SCA8 transcript is an antisense RNA to a brain-specific transcript encoding a novel actin-binding protein (KLHL1)., Hum. Mol. Genet.
- Koob (1999), An untranslated CTG expansion causes a novel form of spinocerebellar ataxia (SCA8), Nat. Genet.
LNCipedia transcript ID history
LNCipedia version | LNCipedia transcript ID |
---|---|
3.1 | lnc-BORA-3:2 |
4.0 | ATXN8OS:6 |
4.1 | ATXN8OS:6 |
5.0 | ATXN8OS:6 |
5.1 | ATXN8OS:6 |
5.2 | ATXN8OS:6 |