Transcript: BDNF-AS:23

Basic information

LNCipedia transcript ID: BDNF-AS:23 
HGNC Gene Symbol: BDNF-AS    
HGNC Full Gene Name: BDNF antisense RNA
Ensembl Gene ID: ENSG00000245573
Ensembl Transcript ID: ENST00000501663
Location (hg38): chr11:27665260-27677807
Strand: +
Class: antisense
Sequence Ontology term: antisense_lncRNA
Transcript size: 959 bp
Exons: 2
Sources: Biogazelle lncRNA chip; Ensembl release 64 - Sep 2011; Gencode v13; Ensembl release 68 - Jul 2012; NONCODE v4; Ensembl release 75 - Feb 2014; Ensembl release 83 - Dec 2015; Ensembl release 87 - Dec 2016; Ensembl release 90 - Aug 2017; Ensembl release 92 - Apr 2018
Alternative transcript names: ENST00000501663; ENST00000501663.2; BDNF-AS-011; OTTHUMT00000388073.1; NONHSAT018526
Alternative gene names: ENSG00000245573; AC104563.1; ENSG00000245573.3; BDNF-AS; OTTHUMG00000166125.5; ENSG00000245573.7; BT2A; BT2B; BT2C; BT2D; NCRNA00049; BDNF-AS1


RNA sequence:

Structure:

Protein coding potential

Metric Raw result Interpretation
PRIDE reprocessing 2.0 0 non-coding 
Lee translation initiation sites 0 non-coding 
PhyloCSF score 7.4959 non-coding 
CPAT coding probability 0.64% non-coding 
Bazzini small ORFs 0 non-coding 

In stringent set: yes

Locus conservation

Locus conservation?
BDNF-AS:23 no no no no

Available literature

  1. Zhong (2017), Knockdown of long noncoding antisense RNA brain-derived neurotrophic factor attenuates hypoxia/reoxygenation-induced nerve cell apoptosis through the BDNF-TrkB-PI3K/Akt signaling pathway., Neuroreport
  2. Magistri (2015), Transcriptomics Profiling of Alzheimer's Disease Reveal Neurovascular Defects, Altered Amyloid-β Homeostasis, and Deregulated Expression of Long Noncoding RNAs., J. Alzheimers Dis.
  3. Pedram Fatemi (2015), Screening for Small-Molecule Modulators of Long Noncoding RNA-Protein Interactions Using AlphaScreen., J Biomol Screen
  4. Wang (2015), Genome-wide differential expression of synaptic long noncoding RNAs in autism spectrum disorder., Transl Psychiatry
  5. Kapusta (2013), Transposable elements are major contributors to the origin, diversification, and regulation of vertebrate long noncoding RNAs., PLoS Genet.
  6. Modarresi (2012), Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation., Nat. Biotechnol.
  7. Liu (2005), Human brain derived neurotrophic factor (BDNF) genes, splicing patterns, and assessments of associations with substance abuse and Parkinson's Disease., Am. J. Med. Genet. B Neuropsychiatr. Genet.


LNCipedia transcript ID history

LNCipedia version LNCipedia transcript ID
1.3 lnc-BBOX1-1:10
3.1 lnc-METTL15-4:10
4.0 BDNF-AS:23
4.1 BDNF-AS:23
5.0 BDNF-AS:23
5.1 BDNF-AS:23
5.2 BDNF-AS:23