Transcript: CCAT2:3

Basic information

LNCipedia transcript ID: CCAT2:3 
HGNC Gene Symbol: CCAT2    
HGNC Full Gene Name: colon cancer associated transcript 2
Ensembl Gene ID: ENSG00000280997
Ensembl Transcript ID: ENST00000630920
RefSeq ID: NR_109834
Location (hg38): chr8:127400399-127402150
Strand: +
Class: intronic
Sequence Ontology term: sense_intronic_ncRNA
Transcript size: 1752 bp
Exons: 1
Sources: Refseq - Dec 2014; Ensembl release 83 - Dec 2015; Ensembl release 87 - Dec 2016; Ensembl release 90 - Aug 2017; Ensembl release 92 - Apr 2018; Refseq - NCBI Annotation Release 106
Alternative transcript names: NR_109834; ENST00000630920.1; NR_109834.1
Alternative gene names: ENSG00000280997.1; CCAT2


RNA sequence:

Structure:

Protein coding potential

Metric Raw result Interpretation
PRIDE reprocessing 2.0 0 non-coding 
Lee translation initiation sites 0 non-coding 
PhyloCSF score -101.6915 non-coding 
CPAT coding probability 0.61% non-coding 
Bazzini small ORFs 0 non-coding 

In stringent set: yes

Locus conservation

Locus conservation?
CCAT2:3 no no no no

Available literature

  1. Thorenoor (2016), Long non-coding RNA ZFAS1 interacts with CDK1 and is involved in p53-dependent cell cycle control and apoptosis in colorectal cancer., Oncotarget
  2. Xie (2016), Long non-coding RNAs in colorectal cancer., Oncotarget
  3. Al-Tassan (2015), A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer., Sci Rep
  4. Cai (2015), Long noncoding RNA CCAT2 promotes breast tumor growth by regulating the Wnt signaling pathway., Onco Targets Ther
  5. Qiu (2015), A novel lncRNA, LUADT1, promotes lung adenocarcinoma proliferation via the epigenetic suppression of p27., Cell Death Dis
  6. Ragusa (2015), Non-coding landscapes of colorectal cancer., World J. Gastroenterol.
  7. Richards (2015), A functional variant in HOXA11-AS, a novel long non-coding RNA, inhibits the oncogenic phenotype of epithelial ovarian cancer., Oncotarget
  8. Sugihara (2015), Noncoding RNA Expression Aberration Is Associated with Cancer Progression and Is a Potential Biomarker in Esophageal Squamous Cell Carcinoma., Int J Mol Sci
  9. Wang (2015), Long non-coding RNA CCAT2 is up-regulated in gastric cancer and associated with poor prognosis., Int J Clin Exp Pathol
  10. Ye (2015), Expression of lncRNA-CCAT1, E-cadherin and N-cadherin in colorectal cancer and its clinical significance., Int J Clin Exp Med
  11. Zhang (2015), Elevated expression of CCAT2 is associated with poor prognosis in esophageal squamous cell carcinoma., J Surg Oncol
  12. Hu (2014), A functional genomic approach identifies FAL1 as an oncogenic long noncoding RNA that associates with BMI1 and represses p21 expression in cancer., Cancer Cell
  13. Qiu (2014), CCAT2 is a lung adenocarcinoma-specific long non-coding RNA and promotes invasion of non-small cell lung cancer., Tumour Biol.
  14. Ling (2013), CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer., Genome Res.
  15. Ling (2013), MicroRNAs and other non-coding RNAs as targets for anticancer drug development., Nat Rev Drug Discov
  16. Redis (2013), CCAT2, a novel long non-coding RNA in breast cancer: expression study and clinical correlations., Oncotarget


LNCipedia transcript ID history

LNCipedia version LNCipedia transcript ID
3.1 lnc-POU5F1B-8:1
4.0 lnc-POU5F1B-8:1
4.1 lnc-POU5F1B-8:1
5.0 lnc-POU5F1B-8:1
5.1 CCAT2:2
5.2 CCAT2:3