Transcript: H19:23

Basic information

LNCipedia transcript ID: H19:23 
HGNC Gene Symbol: H19    
HGNC Full Gene Name: H19, imprinted maternally expressed transcript
Ensembl Gene ID: ENSG00000130600
Ensembl Transcript ID: ENST00000643292
Location (hg38): chr11:1997076-1997875
Strand: -
Class: intergenic
Sequence Ontology term: lincRNA
Transcript size: 475 bp
Exons: 2
Sources: Ensembl release 92 - Apr 2018
Alternative transcript names: ENST00000643292.1
Alternative gene names: ENSG00000130600.18; H19


RNA sequence:

Structure:

Protein coding potential

Metric Raw result Interpretation
PRIDE reprocessing 2.0 0 non-coding 
Lee translation initiation sites non-coding 
PhyloCSF score -499.6989 non-coding 
CPAT coding probability 2.51% non-coding 
Bazzini small ORFs 0 non-coding 

In stringent set: yes

Locus conservation

Locus conservation?
H19:23 no no no no

Available literature

  1. Han (2016), Circulating long noncoding RNA GAS5 as a potential biomarker in breast cancer for assessing the surgical effects., Tumour Biol.
  2. Jiang (2016), Increased level of H19 long noncoding RNA promotes invasion, angiogenesis, and stemness of glioblastoma cells., J. Neurosurg.
  3. Kanduri (2016), Long noncoding RNAs: Lessons from genomic imprinting., Biochim. Biophys. Acta
  4. Liu (2016), H19-derived miR-675 contributes to bladder cancer cell proliferation by regulating p53 activation., Tumour Biol.
  5. Matouk (2016), The role of the oncofetal H19 lncRNA in tumor metastasis: orchestrating the EMT-MET decision., Oncotarget
  6. Wang (2016), Differential lncRNA‑mRNA co‑expression network analysis revealing the potential regulatory roles of lncRNAs in myocardial infarction., Mol Med Rep
  7. Xie (2016), Long non-coding RNAs in colorectal cancer., Oncotarget
  8. Zhang (2016), Long non-coding RNA chromogenic in situ hybridisation signal pattern correlation with breast tumour pathology., J. Clin. Pathol.
  9. Zhang (2016), c-Myc-regulated long non-coding RNA H19 indicates a poor prognosis and affects cell proliferation in non-small-cell lung cancer., Tumour Biol.
  10. Zhang (2016), Erratum to: c-Myc-regulated long non-coding RNA H19 indicates a poor prognosis and affects cell proliferation in non-small-cell lung cancer., Tumour Biol.
  11. Bauderlique-Le Roy (2015), Enrichment of Human Stem-Like Prostate Cells with s-SHIP Promoter Activity Uncovers a Role in Stemness for the Long Noncoding RNA H19., Stem Cells Dev.
  12. Bida (2015), A novel mitosis-associated lncRNA, MA-linc1, is required for cell cycle progression and sensitizes cancer cells to Paclitaxel., Oncotarget
  13. Bo (2015), Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma., Oncotarget
  14. Carter (2015), Circulating long noncoding RNA GAS5 levels are correlated to prevalence of type 2 diabetes mellitus., BBA Clin
  15. Chen (2015), Constructing lncRNA functional similarity network based on lncRNA-disease associations and disease semantic similarity., Sci Rep
  16. Chen (2015), Differential lncRNA expression profiles in recurrent gliomas compared with primary gliomas identified by microarray analysis., Int J Clin Exp Med
  17. Chen (2015), Predicting lncRNA-disease associations and constructing lncRNA functional similarity network based on the information of miRNA., Sci Rep
  18. Conigliaro (2015), CD90+ liver cancer cells modulate endothelial cell phenotype through the release of exosomes containing H19 lncRNA., Mol. Cancer
  19. Ding (2015), Long non-coding RNA PVT1 is associated with tumor progression and predicts recurrence in hepatocellular carcinoma patients., Oncol Lett
  20. Du (2015), The association analysis of lncRNA HOTAIR genetic variants and gastric cancer risk in a Chinese population., Oncotarget
  21. Gao (2015), Association of polymorphisms in long non-coding RNA H19 with coronary artery disease risk in a Chinese population., Mutat. Res.
  22. Ge (2015), MiRNA-192 [corrected] and miRNA-204 Directly Suppress lncRNA HOTTIP and Interrupt GLS1-Mediated Glutaminolysis in Hepatocellular Carcinoma., PLoS Genet.
  23. Ghazal (2015), H19 lncRNA alters stromal cell growth via IGF signaling in the endometrium of women with endometriosis., EMBO Mol Med
  24. Glover (2015), Long noncoding RNA profiles of adrenocortical cancer can be used to predict recurrence., Endocr. Relat. Cancer
  25. Guo (2015), Competing endogenous RNA networks and gastric cancer., World J. Gastroenterol.
  26. He (2015), LongTarget: a tool to predict lncRNA DNA-binding motifs and binding sites via Hoogsteen base-pairing analysis., Bioinformatics
  27. Hewage (2015), H19 rs217727 genotype and IGF-1/intron -2 dinucleotide CT repeat polymorphism are independently associated with birth weight., Endocrine
  28. Huang (2015), Upregulation of H19 promotes invasion and induces epithelial-to-mesenchymal transition in esophageal cancer., Oncol Lett
  29. Huang (2015), HBx-related long non-coding RNA DBH-AS1 promotes cell proliferation and survival by activating MAPK signaling in hepatocellular carcinoma., Oncotarget
  30. Huang (2015), Long Noncoding RNA H19 Promotes Osteoblast Differentiation Via TGF-β1/Smad3/HDAC Signaling Pathway by Deriving miR-675., Stem Cells
  31. Imig (2015), miR-CLIP capture of a miRNA targetome uncovers a lincRNA H19-miR-106a interaction., Nat. Chem. Biol.
  32. Jiang (2015), LncRNA2Function: a comprehensive resource for functional investigation of human lncRNAs based on RNA-seq data., BMC Genomics
  33. Jiang (2015), Long non-coding RNA profiling links subgroup classification of endometrioid endometrial carcinomas with trithorax and polycomb complex aberrations., Oncotarget
  34. Kraus (2015), Identification of Stably Expressed lncRNAs as Valid Endogenous Controls for Profiling of Human Glioma., J Cancer
  35. Li (2015), MDR1 will play a key role in pharmacokinetic changes under hypoxia at high altitude and its potential regulatory networks., Drug Metab. Rev.
  36. Li (2015), The YAP1 oncogene contributes to bladder cancer cell proliferation and migration by regulating the H19 long noncoding RNA., Urol. Oncol.
  37. Li (2015), miR675 upregulates long noncoding RNA H19 through activating EGR1 in human liver cancer., Oncotarget
  38. Li (2015), LncRNA ontology: inferring lncRNA functions based on chromatin states and expression patterns., Oncotarget
  39. Li (2015), H19 derived microRNA-675 regulates cell proliferation and migration through CDK6 in glioma., Am J Transl Res
  40. Liang (2015), The lncRNA H19 promotes epithelial to mesenchymal transition by functioning as miRNA sponges in colorectal cancer., Oncotarget
  41. Liu (2015), Carboplatin-docetaxel-induced activity against ovarian cancer is dependent on up-regulated lncRNA PVT1., Int J Clin Exp Pathol
  42. Malouf (2015), Characterization of long non-coding RNA transcriptome in clear-cell renal cell carcinoma by next-generation deep sequencing., Mol Oncol
  43. Martínez-Fernández (2015), EZH2 in Bladder Cancer, a Promising Therapeutic Target., Int J Mol Sci
  44. Na (2015), Long non-coding RNA UCA1 contributes to the progression of prostate cancer and regulates proliferation through KLF4-KRT6/13 signaling pathway., Int J Clin Exp Med
  45. Pastori (2015), The Bromodomain protein BRD4 controls HOTAIR, a long noncoding RNA essential for glioblastoma proliferation., Proc. Natl. Acad. Sci. U.S.A.
  46. Pei (2015), Notch-1 promotes breast cancer cells proliferation by regulating LncRNA GAS5., Int J Clin Exp Med
  47. Prickett (2015), Genome-wide methylation analysis in Silver-Russell syndrome patients., Hum. Genet.
  48. Pu (2015), CUDR promotes liver cancer stem cell growth through upregulating TERT and C-Myc., Oncotarget
  49. Quek (2015), lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs., Nucleic Acids Res.
  50. Ragusa (2015), Non-coding landscapes of colorectal cancer., World J. Gastroenterol.
  51. Raveh (2015), The H19 Long non-coding RNA in cancer initiation, progression and metastasis - a proposed unifying theory., Mol. Cancer
  52. Richards (2015), A functional variant in HOXA11-AS, a novel long non-coding RNA, inhibits the oncogenic phenotype of epithelial ovarian cancer., Oncotarget
  53. Shen (2015), Exploration of Deregulated Long Non-Coding RNAs in Association with Hepatocarcinogenesis and Survival., Cancers (Basel)
  54. Shi (2015), Microvascular invasion in hepatocellular carcinoma overexpression promotes cell proliferation and inhibits cell apoptosis of hepatocellular carcinoma via inhibiting miR-199a expression., Onco Targets Ther
  55. Smolle (2015), Long Non-Coding RNAs in Endometrial Carcinoma., Int J Mol Sci
  56. Sun (2015), H19 lncRNA mediates 17β-estradiol-induced cell proliferation in MCF-7 breast cancer cells., Oncol. Rep.
  57. Tan (2015), Reprogramming during epithelial to mesenchymal transition under the control of TGFβ., Cell Adh Migr
  58. Tantai (2015), Combined identification of long non-coding RNA XIST and HIF1A-AS1 in serum as an effective screening for non-small cell lung cancer., Int J Clin Exp Pathol
  59. Vennin (2015), H19 non coding RNA-derived miR-675 enhances tumorigenesis and metastasis of breast cancer cells by downregulating c-Cbl and Cbl-b., Oncotarget
  60. Wan (2015), The functional sites of miRNAs and lncRNAs in gastric carcinogenesis., Tumour Biol.
  61. Wang (2015), Differential expression of long noncoding ribonucleic acids during osteogenic differentiation of human bone marrow mesenchymal stem cells., Int Orthop
  62. Wang (2015), Down-regulated long non-coding RNA H19 inhibits carcinogenesis of renal cell carcinoma., Neoplasma
  63. Wang (2015), MicroRNA-103/107 Regulate Programmed Necrosis and Myocardial Ischemia/Reperfusion Injury Through Targeting FADD., Circ. Res.
  64. Wang (2015), Genome-scale long noncoding RNA expression pattern in squamous cell lung cancer., Sci Rep
  65. Wang (2015), Upregulated lncRNA-UCA1 contributes to progression of lung cancer and is closely related to clinical diagnosis as a predictive biomarker in plasma., Int J Clin Exp Med
  66. Wang (2015), Serum LncRNAs Profiles Serve as Novel Potential Biomarkers for the Diagnosis of HBV-Positive Hepatocellular Carcinoma., PLoS ONE
  67. Wei (2015), Transcriptome profiling of esophageal squamous cell carcinoma reveals a long noncoding RNA acting as a tumor suppressor., Oncotarget
  68. Wu (2015), Analysis of differentially expressed lncRNAs in differentiation of bone marrow stem cells into neural cells., J. Neurol. Sci.
  69. Wu (2015), The long non-coding RNA HNF1A-AS1 regulates proliferation and metastasis in lung adenocarcinoma., Oncotarget
  70. Yan (2015), Regulation of tumor cell migration and invasion by the H19/let-7 axis is antagonized by metformin-induced DNA methylation., Oncogene
  71. Yang (2015), Tag SNPs in long non-coding RNA H19 contribute to susceptibility to gastric cancer in the Chinese Han population., Oncotarget
  72. Yang (2015), LincRNA-p21 activates endoplasmic reticulum stress and inhibits hepatocellular carcinoma., Oncotarget
  73. Yu (2015), Long non-coding RNAs and hepatocellular carcinoma., Mol Clin Oncol
  74. Zeira (2015), The knockdown of H19lncRNA reveals its regulatory role in pluripotency and tumorigenesis of human embryonic carcinoma cells., Oncotarget
  75. Zhang (2015), LncRNA MALAT1 overexpression is an unfavorable prognostic factor in human cancer: evidence from a meta-analysis., Int J Clin Exp Med
  76. Zhang (2015), Cancer Specific Long Noncoding RNAs Show Differential Expression Patterns and Competing Endogenous RNA Potential in Hepatocellular Carcinoma., PLoS ONE
  77. Zhao (2015), Knockdown of a novel lincRNA AATBC suppresses proliferation and induces apoptosis in bladder cancer., Oncotarget
  78. Zhao (2015), Long non-coding RNA Linc00152 is involved in cell cycle arrest, apoptosis, epithelial to mesenchymal transition, cell migration and invasion in gastric cancer., Cell Cycle
  79. Zhi (2015), The Use of Three Long Non-Coding RNAs as Potential Prognostic Indicators of Astrocytoma., PLoS ONE
  80. Zhou (2015), Identification of the long non-coding RNA H19 in plasma as a novel biomarker for diagnosis of gastric cancer., Sci Rep
  81. Zhou (2015), The Interaction Between MiR-141 and lncRNA-H19 in Regulating Cell Proliferation and Migration in Gastric Cancer., Cell. Physiol. Biochem.
  82. Zhou (2015), H19 lncRNA alters DNA methylation genome wide by regulating S-adenosylhomocysteine hydrolase., Nat Commun
  83. Zhu (2015), Ectopic expressed long non-coding RNA H19 contributes to malignant cell behavior of ovarian cancer., Int J Clin Exp Pathol
  84. Chan (2014), Hedgehog signaling induces osteosarcoma development through Yap1 and H19 overexpression., Oncogene
  85. Cordeiro (2014), Relevance of genomic imprinting in intrauterine human growth expression of CDKN1C, H19, IGF2, KCNQ1 and PHLDA2 imprinted genes., J. Assist. Reprod. Genet.
  86. Das (2014), lnCeDB: database of human long noncoding RNA acting as competing endogenous RNA., PLoS ONE
  87. Dey (2014), The H19 long noncoding RNA gives rise to microRNAs miR-675-3p and miR-675-5p to promote skeletal muscle differentiation and regeneration., Genes Dev.
  88. Feng (2014), Methods for the study of long noncoding RNA in cancer cell signaling., Methods Mol. Biol.
  89. Gao (2014), The H19/let-7 double-negative feedback loop contributes to glucose metabolism in muscle cells., Nucleic Acids Res.
  90. Guo (2014), An integrated evolutionary analysis of miRNA-lncRNA in mammals., Mol. Biol. Rep.
  91. Guo (2014), High expression of long non-coding RNA H19 is required for efficient tumorigenesis induced by Bcr-Abl oncogene., FEBS Lett.
  92. Guo (2014), BRAF-activated long non-coding RNA contributes to colorectal cancer migration by inducing epithelial-mesenchymal transition., Oncol Lett
  93. Higashimoto (2014), A novel de novo point mutation of the OCT-binding site in the IGF2/H19-imprinting control region in a Beckwith-Wiedemann syndrome patient., Clin. Genet.
  94. Hou (2014), Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients., PLoS ONE
  95. Kernohan (2014), Analysis of neonatal brain lacking ATRX or MeCP2 reveals changes in nucleosome density, CTCF binding and chromatin looping., Nucleic Acids Res.
  96. Kim (2014), Reduced MiR-675 in exosome in H19 RNA-related melanogenesis via MITF as a direct target., J. Invest. Dermatol.
  97. Kong (2014), Quantitative assessment of short amplicons in FFPE-derived long-chain RNA., Sci Rep
  98. Lau (2014), Viral-human chimeric transcript predisposes risk to liver cancer development and progression., Cancer Cell
  99. Li (2014), Overexpression of lncRNA H19 enhances carcinogenesis and metastasis of gastric cancer., Oncotarget
  100. Li (2014), Non-coding RNAs and gastric cancer., World J. Gastroenterol.
  101. Lin (2014), Long noncoding RNA expression in dermal papilla cells contributes to hairy gene regulation., Biochem. Biophys. Res. Commun.
  102. Liu (2014), Vigilin interacts with CCCTC-binding factor (CTCF) and is involved in CTCF-dependent regulation of the imprinted genes Igf2 and H19., FEBS J.
  103. Lu (2014), Methylation pattern of H19 exon 1 is closely related to preeclampsia and trophoblast abnormalities., Int. J. Mol. Med.
  104. Lv (2014), Downregulation of LncRNAH19 and MiR-675 promotes migration and invasion of human hepatocellular carcinoma cells through AKT/GSK-3β/Cdc25A signaling pathway., J. Huazhong Univ. Sci. Technol. Med. Sci.
  105. Ma (2014), Intragenic microRNA and long non-coding RNA: novel potential regulator of IGF2-H19 imprinting region., Evol. Dev.
  106. Ma (2014), H19 promotes pancreatic cancer metastasis by derepressing let-7's suppression on its target HMGA2-mediated EMT., Tumour Biol.
  107. Mathiyalagan (2014), Interplay of chromatin modifications and non-coding RNAs in the heart., Epigenetics
  108. Matouk (2014), Oncofetal H19 RNA promotes tumor metastasis., Biochim. Biophys. Acta
  109. Medrzycki (2014), Histone h1.3 suppresses h19 noncoding RNA expression and cell growth of ovarian cancer cells., Cancer Res.
  110. Pestell (2014), Long and noncoding RNAs (lnc-RNAs) determine androgen receptor dependent gene expression in prostate cancer growth in vivo., Asian J. Androl.
  111. Prensner (2014), The long non-coding RNA PCAT-1 promotes prostate cancer cell proliferation through cMyc., Neoplasia
  112. Quagliata (2014), Long noncoding RNA HOTTIP/HOXA13 expression is associated with disease progression and predicts outcome in hepatocellular carcinoma patients., Hepatology
  113. Ravid (2014), Relative genomic stability of adipose tissue derived mesenchymal stem cells: analysis of ploidy, H19 long non-coding RNA and p53 activity., Stem Cell Res Ther
  114. Rogler (2014), Small RNAs derived from lncRNA RNase MRP have gene-silencing activity relevant to human cartilage-hair hypoplasia., Hum. Mol. Genet.
  115. Schneider (2014), The paternally imprinted DLK1-GTL2 locus is differentially methylated in embryonal and alveolar rhabdomyosarcomas., Int. J. Oncol.
  116. Shao (2014), Gastric juice long noncoding RNA used as a tumor marker for screening gastric cancer., Cancer
  117. Shi (2014), Long non-coding RNA H19 promotes glioma cell invasion by deriving miR-675., PLoS ONE
  118. Su (2014), Comprehensive analysis of long non-coding RNAs in human breast cancer clinical subtypes., Oncotarget
  119. Uh (2014), Analysis of imprinted IGF2/H19 gene methylation and expression in normal fertilized and parthenogenetic embryonic stem cells of pigs., Anim. Reprod. Sci.
  120. Wang (2014), Exploring the stability of long intergenic non-coding RNA in K562 cells by comparative studies of RNA-Seq datasets., Biol. Direct
  121. Wang (2014), MDRL lncRNA regulates the processing of miR-484 primary transcript by targeting miR-361., PLoS Genet.
  122. Xia (2014), Long noncoding RNA associated-competing endogenous RNAs in gastric cancer., Sci Rep
  123. Xing (2014), Identification of long noncoding RNA associated with osteoarthritis in humans., Orthop Surg
  124. Yang (2014), A network based method for analysis of lncRNA-disease associations and prediction of lncRNAs implicated in diseases., PLoS ONE
  125. Zhang (2014), c-Myc-induced, long, noncoding H19 affects cell proliferation and predicts a poor prognosis in patients with gastric cancer., Med. Oncol.
  126. Zhang (2014), Comparative DNA methylome analysis of endometrial carcinoma reveals complex and distinct deregulation of cancer promoters and enhancers., BMC Genomics
  127. Zhou (2014), An emerging understanding of long noncoding RNAs in kidney cancer., J. Cancer Res. Clin. Oncol.
  128. Zhu (2014), lncRNA H19/miR-675 axis represses prostate cancer metastasis by targeting TGFBI., FEBS J.
  129. Zhuang (2014), The long non-coding RNA H19-derived miR-675 modulates human gastric cancer cell proliferation by targeting tumor suppressor RUNX1., Biochem. Biophys. Res. Commun.
  130. van Heesch (2014), Extensive localization of long noncoding RNAs to the cytosol and mono- and polyribosomal complexes., Genome Biol.
  131. Akrami (2013), Comprehensive analysis of long non-coding RNAs in ovarian cancer reveals global patterns and targeted DNA amplification., PLoS ONE
  132. Ankolkar (2013), Methylation status of imprinted genes DLK1-GTL2, MEST (PEG1), ZAC (PLAGL1), and LINE-1 elements in spermatozoa of normozoospermic men, unlike H19 imprinting control regions, is not associated with idiopathic recurrent spontaneous miscarriages., Fertil. Steril.
  133. Arita (2013), Circulating long non-coding RNAs in plasma of patients with gastric cancer., Anticancer Res.
  134. Atala (2013), Re: Long non-coding RNA H19 increases bladder cancer metastasis by associating with EZH2 and inhibiting E-cadherin expression., J. Urol.
  135. Bhan (2013), Antisense transcript long noncoding RNA (lncRNA) HOTAIR is transcriptionally induced by estradiol., J. Mol. Biol.
  136. Bi (2013), H19 inhibits RNA polymerase II-mediated transcription by disrupting the hnRNP U-actin complex., Biochim. Biophys. Acta
  137. Bouwland-Both (2013), DNA methylation of IGF2DMR and H19 is associated with fetal and infant growth: the generation R study., PLoS ONE
  138. Chaiworapongsa (2013), Differences and similarities in the transcriptional profile of peripheral whole blood in early and late-onset preeclampsia: insights into the molecular basis of the phenotype of preeclampsiaa., J Perinat Med
  139. Chen (2013), Mdig de-represses H19 large intergenic non-coding RNA (lincRNA) by down-regulating H3K9me3 and heterochromatin., Oncotarget
  140. Du (2013), Integrative genomic analyses reveal clinically relevant long noncoding RNAs in human cancer., Nat. Struct. Mol. Biol.
  141. Goodell (2013), Parental permissions: H19 and keeping the stem cell progeny under control., Cell Stem Cell
  142. Kallen (2013), The imprinted H19 lncRNA antagonizes let-7 microRNAs., Mol. Cell
  143. Kogure (2013), Extracellular Vesicle-Mediated Transfer of a Novel Long Noncoding RNA TUC339: A Mechanism of Intercellular Signaling in Human Hepatocellular Cancer., Genes Cancer
  144. Kung (2013), RNA in the loop., Dev. Cell
  145. Li (2013), [Correlation of DNA methylation status of imprinted gene H19 ICR with oligozoospermia and asthenozoospermia]., Zhonghua Nan Ke Xue
  146. Li (2013), Targeted disruption of Hotair leads to homeotic transformation and gene derepression., Cell Rep
  147. Li (2013), Association between polymorphisms in long non-coding RNA PRNCR1 in 8q24 and risk of colorectal cancer., J. Exp. Clin. Cancer Res.
  148. Liu (2013), Downregulation of GAS5 promotes bladder cancer cell proliferation, partly by regulating CDK6., PLoS ONE
  149. Liu (2013), Identification of differentially expressed long non-coding RNAs in human ovarian cancer cells with different metastatic potentials., Cancer Biol Med
  150. Loke (2013), Association of maternal and nutrient supply line factors with DNA methylation at the imprinted IGF2/H19 locus in multiple tissues of newborn twins., Epigenetics
  151. Luo (2013), Long non-coding RNA H19 increases bladder cancer metastasis by associating with EZH2 and inhibiting E-cadherin expression., Cancer Lett.
  152. Luo (2013), Upregulated H19 contributes to bladder cancer cell proliferation by regulating ID2 expression., FEBS J.
  153. McGraw (2013), Loss of DNMT1o disrupts imprinted X chromosome inactivation and accentuates placental defects in females., PLoS Genet.
  154. Monnier (2013), [H19 gene controls placental development through a miRNA]., Med Sci (Paris)
  155. Nelissen (2013), Placentas from pregnancies conceived by IVF/ICSI have a reduced DNA methylation level at the H19 and MEST differentially methylated regions., Hum. Reprod.
  156. Nie (2013), Long non-coding RNA HOTAIR is an independent prognostic marker for nasopharyngeal carcinoma progression and survival., Cancer Sci.
  157. Papait (2013), Long noncoding RNA: a new player of heart failure?, J Cardiovasc Transl Res
  158. Qiao (2013), Long non-coding RNA GAS5 functions as a tumor suppressor in renal cell carcinoma., Asian Pac. J. Cancer Prev.
  159. Qiu (2013), Long noncoding RNA: an emerging paradigm of cancer research., Tumour Biol.
  160. Rusiecki (2013), PTSD and DNA Methylation in Select Immune Function Gene Promoter Regions: A Repeated Measures Case-Control Study of U.S. Military Service Members., Front Psychiatry
  161. Sheffield (2013), Patterns of regulatory activity across diverse human cell types predict tissue identity, transcription factor binding, and long-range interactions., Genome Res.
  162. Song (2013), Long non-coding RNA expression profile in human gastric cancer and its clinical significances., J Transl Med
  163. Soubry (2013), Paternal obesity is associated with IGF2 hypomethylation in newborns: results from a Newborn Epigenetics Study (NEST) cohort., BMC Med
  164. Sánchez (2013), Long non-coding RNAs: challenges for diagnosis and therapies., Nucleic Acid Ther
  165. Tang (2013), Long noncoding RNAs-related diseases, cancers, and drugs., ScientificWorldJournal
  166. Wan (2013), Long non-coding RNA ANRIL (CDKN2B-AS) is induced by the ATM-E2F1 signaling pathway., Cell. Signal.
  167. Wang (2013), Zbtb7a suppresses prostate cancer through repression of a Sox9-dependent pathway for cellular senescence bypass and tumor invasion., Nat. Genet.
  168. Zhang (2013), Epigenetic activation of the MiR-200 family contributes to H19-mediated metastasis suppression in hepatocellular carcinoma., Carcinogenesis
  169. Zou (2013), Upregulation of long noncoding RNA SPRY4-IT1 modulates proliferation, migration, apoptosis, and network formation in trophoblast cells HTR-8SV/neo., PLoS ONE
  170. Akhtar (2012), Cell type and context-specific function of PLAG1 for IGF2 P3 promoter activity., Int. J. Oncol.
  171. Ankolkar (2012), Methylation analysis of idiopathic recurrent spontaneous miscarriage cases reveals aberrant imprinting at H19 ICR in normozoospermic individuals., Fertil. Steril.
  172. Buckberry (2012), Quantitative allele-specific expression and DNA methylation analysis of H19, IGF2 and IGF2R in the human placenta across gestation reveals H19 imprinting plasticity., PLoS ONE
  173. Bánfai (2012), Long noncoding RNAs are rarely translated in two human cell lines., Genome Res.
  174. Derrien (2012), The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression., Genome Res.
  175. Gascoigne (2012), Pinstripe: a suite of programs for integrating transcriptomic and proteomic datasets identifies novel proteins and improves differentiation of protein-coding and non-coding genes., Bioinformatics
  176. Herold (2012), CTCF: insights into insulator function during development., Development
  177. Higashimoto (2012), Aberrant methylation of H19-DMR acquired after implantation was dissimilar in soma versus placenta of patients with Beckwith-Wiedemann syndrome., Am. J. Med. Genet. A
  178. Keniry (2012), The H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and Igf1r., Nat. Cell Biol.
  179. Nagy (2012), [Relevance of long non-coding RNAs in tumour biology]., Orv Hetil
  180. Niazi (2012), Computational analysis of functional long noncoding RNAs reveals lack of peptide-coding capacity and parallels with 3' UTRs., RNA
  181. Ragina (2012), Downregulation of H19 improves the differentiation potential of mouse parthenogenetic embryonic stem cells., Stem Cells Dev.
  182. Shoshani (2012), Polyploidization of murine mesenchymal cells is associated with suppression of the long noncoding RNA H19 and reduced tumorigenicity., Cancer Res.
  183. St-Pierre (2012), IGF2 DNA methylation is a modulator of newborn's fetal growth and development., Epigenetics
  184. Steck (2012), Regulation of H19 and its encoded microRNA-675 in osteoarthritis and under anabolic and catabolic in vitro conditions., J. Mol. Med.
  185. Tilgner (2012), Deep sequencing of subcellular RNA fractions shows splicing to be predominantly co-transcriptional in the human genome but inefficient for lncRNAs., Genome Res.
  186. Troy (2012), Genetic "lnc"-age of noncoding RNAs to human disease., J. Clin. Invest.
  187. Yang (2012), Up-regulated long non-coding RNA H19 contributes to proliferation of gastric cancer cells., FEBS J.
  188. Al-Khtib (2011), Vitrification at the germinal vesicle stage does not affect the methylation profile of H19 and KCNQ1OT1 imprinting centers in human oocytes subsequently matured in vitro., Fertil. Steril.
  189. Braconi (2011), microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer., Oncogene
  190. Braunschweig (2011), Relationship of porcine IGF2 imprinting status to DNA methylation at the H19 DMD and the IGF2 DMRs 1 and 2., BMC Genet.
  191. De Crescenzo (2011), A novel microdeletion in the IGF2/H19 imprinting centre region defines a recurrent mutation mechanism in familial Beckwith-Wiedemann syndrome., Eur J Med Genet
  192. El Hajj (2011), Methylation status of imprinted genes and repetitive elements in sperm DNA from infertile males., Sex Dev
  193. Gao (2011), Detection of global DNA methylation and paternally imprinted H19 gene methylation in preeclamptic placentas., Hypertens. Res.
  194. Grønskov (2011), Deletions and rearrangements of the H19/IGF2 enhancer region in patients with Silver-Russell syndrome and growth retardation., J. Med. Genet.
  195. Hubertus (2011), Altered expression of imprinted genes in Wilms tumors., Oncol. Rep.
  196. Ideraabdullah (2011), Novel cis-regulatory function in ICR-mediated imprinted repression of H19., Dev. Biol.
  197. Knowling (2011), Non-coding RNA and antisense RNA. Nature's trash or treasure?, Biochimie
  198. Lin (2011), Nonallelic transcriptional roles of CTCF and cohesins at imprinted loci., Mol. Cell. Biol.
  199. Minor (2011), Aberrant DNA methylation at imprinted genes in testicular sperm retrieved from men with obstructive azoospermia and undergoing vasectomy reversal., Reproduction
  200. Onyango (2011), A nucleolar protein, H19 opposite tumor suppressor (HOTS), is a tumor growth inhibitor encoded by a human imprinted H19 antisense transcript., Proc. Natl. Acad. Sci. U.S.A.
  201. Sandbacka (2011), Methylation of H19 and its imprinted control region (H19 ICR1) in Müllerian aplasia., Fertil. Steril.
  202. Shi (2011), Abnormal methylation patterns at the IGF2/H19 imprinting control region in phenotypically normal babies conceived by assisted reproductive technologies., Eur. J. Obstet. Gynecol. Reprod. Biol.
  203. Stouder (2011), Specific transgenerational imprinting effects of the endocrine disruptor methoxychlor on male gametes., Reproduction
  204. Stouder (2011), Prenatal exposure to ethanol: a specific effect on the H19 gene in sperm., Reprod. Toxicol.
  205. Xiao (2011), Specific sites in the C terminus of CTCF interact with the SA2 subunit of the cohesin complex and are required for cohesin-dependent insulation activity., Mol. Cell. Biol.
  206. Castle (2010), Digital genome-wide ncRNA expression, including SnoRNAs, across 11 human tissues using polyA-neutral amplification., PLoS ONE
  207. Dudek (2010), Type II collagen expression is regulated by tissue-specific miR-675 in human articular chondrocytes., J. Biol. Chem.
  208. Gabory (2010), The H19 locus: role of an imprinted non-coding RNA in growth and development., Bioessays
  209. Göndör (2010), Window into the complexities of chromosome interactomes., Cold Spring Harb. Symp. Quant. Biol.
  210. Tsang (2010), Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer., Carcinogenesis
  211. Zhao (2010), Genome-wide identification of polycomb-associated RNAs by RIP-seq., Mol. Cell
  212. Gabory (2009), H19 acts as a trans regulator of the imprinted gene network controlling growth in mice., Development
  213. Smits (2008), Conservation of the H19 noncoding RNA and H19-IGF2 imprinting mechanism in therians., Nat. Genet.
  214. Yoshimizu (2008), The H19 locus acts in vivo as a tumor suppressor., Proc. Natl. Acad. Sci. U.S.A.
  215. Cai (2007), The imprinted H19 noncoding RNA is a primary microRNA precursor., RNA
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LNCipedia transcript ID history

LNCipedia version LNCipedia transcript ID
5.0 H19:23
5.1 H19:23
5.2 H19:23