Transcript: JPX:12

Basic information

LNCipedia transcript ID: JPX:12 
HGNC Gene Symbol: JPX    
HGNC Full Gene Name: JPX transcript, XIST activator
Ensembl Gene ID: ENSG00000225470
Ensembl Transcript ID: ENST00000602895
Location (hg38): chrX:73944343-73999503
Strand: +
Class: intergenic
Sequence Ontology term: lincRNA
Transcript size: 829 bp
Exons: 4
Sources: NONCODE v4; Ensembl release 75 - Feb 2014; Ensembl release 83 - Dec 2015; Ensembl release 87 - Dec 2016; Ensembl release 90 - Aug 2017; Ensembl release 92 - Apr 2018
Alternative transcript names: NONHSAT137572; ENST00000602895.1; ENST00000602895.5
Alternative gene names: ENSG00000225470.2; JPX; ENSG00000225470.6; ENOX; LINC00183; DCBALD06; ENSG00000225470.7


RNA sequence:

Structure:

Protein coding potential

Metric Raw result Interpretation
PRIDE reprocessing 2.0 0 non-coding 
Lee translation initiation sites 1 non-coding 
PhyloCSF score 34.3982 non-coding 
CPAT coding probability 2.20% non-coding 
Bazzini small ORFs 0 non-coding 

In stringent set: no

Locus conservation

Locus conservation?
JPX:12 no no no no

Available literature

  1. Soma (2014), Ftx is dispensable for imprinted X-chromosome inactivation in preimplantation mouse embryos., Sci Rep
  2. Takahashi (2014), Extracellular vesicle-mediated transfer of long non-coding RNA ROR modulates chemosensitivity in human hepatocellular cancer., FEBS Open Bio
  3. Ørom (2013), Long noncoding RNAs usher in a new era in the biology of enhancers., Cell
  4. Chureau (2011), Ftx is a non-coding RNA which affects Xist expression and chromatin structure within the X-inactivation center region., Hum. Mol. Genet.
  5. Horvath (2011), Comparative analysis of the primate X-inactivation center region and reconstruction of the ancestral primate XIST locus., Genome Res.
  6. Payer (2011), X-inactivation and X-reactivation: epigenetic hallmarks of mammalian reproduction and pluripotent stem cells., Hum. Genet.
  7. Romito (2011), Origin and evolution of the long non-coding genes in the X-inactivation center., Biochimie
  8. Wang (2011), Molecular mechanisms of long noncoding RNAs., Mol. Cell
  9. Kolesnikov (2010), [Comparative organization and the origin of noncoding regulatory RNA genes from X-chromosome inactivation center of human and mouse]., Genetika
  10. Tian (2010), The long noncoding RNA, Jpx, is a molecular switch for X chromosome inactivation., Cell
  11. Tsai (2008), Higher order chromatin structure at the X-inactivation center via looping DNA., Dev. Biol.
  12. Chureau (2002), Comparative sequence analysis of the X-inactivation center region in mouse, human, and bovine., Genome Res.
  13. Johnston (2002), Enox, a novel gene that maps 10 kb upstream of Xist and partially escapes X inactivation., Genomics


LNCipedia transcript ID history

LNCipedia version LNCipedia transcript ID
3.1 lnc-CHIC1-3:12
4.0 JPX:12
4.1 JPX:12
5.0 JPX:12
5.1 JPX:12
5.2 JPX:12