Transcript: NEAT1:2
Basic information
LNCipedia transcript ID: NEAT1:2
LNCipedia gene ID: NEAT1
Location (hg38): chr11:65419566-65428350
Strand: +
Class: intergenic
Sequence Ontology term: lincRNA
Transcript size: 1913 bp
Exons: 5
Sources: Nielsen et al.,2014
Alternative transcript names: l_496_chr11:65187036-65195821_adrenal
Alternative gene names: TncRNA; MENepsilon/beta; LINC00084; VINC
RNA sequence:
Structure:
Protein coding potential
In stringent set: yes
Locus conservation
Locus conservation? | ||||
---|---|---|---|---|
NEAT1:2 | no | no | no | no |
Available literature
- He (2016), Aberrant NEAT1 expression is associated with clinical outcome in high grade glioma patients., APMIS
- Hu (2016), The plasma lncRNA acting as fingerprint in non-small-cell lung cancer., Tumour Biol.
- Ichigozaki (2016), Serum long non-coding RNA, snoRNA host gene 5 level as a new tumor marker of malignant melanoma., Exp. Dermatol.
- Jin (2016), Detection of the long noncoding RNAs nuclear-enriched autosomal transcript 1 (NEAT1) and metastasis associated lung adenocarcinoma transcript 1 in the peripheral blood of HIV-1-infected patients., HIV Med.
- Lennox (2016), Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides., Nucleic Acids Res.
- Wilusz (2016), Long noncoding RNAs: Re-writing dogmas of RNA processing and stability., Biochim. Biophys. Acta
- Zhen (2016), Long noncoding RNA NEAT1 promotes glioma pathogenesis by regulating miR-449b-5p/c-Met axis., Tumour Biol.
- Barry (2015), Long Non-Coding RNA Expression during Aging in the Human Subependymal Zone., Front Neurol
- Bhattacharyya (2015), The Malat1 long non-coding RNA is upregulated by signalling through the PERK axis of unfolded protein response during flavivirus infection., Sci Rep
- Blume (2015), p53-dependent non-coding RNA networks in chronic lymphocytic leukemia., Leukemia
- Bo (2015), Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma., Oncotarget
- Budhiraja (2015), Mining the human complexome database identifies RBM14 as an XPO1-associated protein involved in HIV-1 Rev function., J. Virol.
- Cabili (2015), Localization and abundance analysis of human lncRNAs at single-cell and single-molecule resolution., Genome Biol.
- Cajigas (2015), Evf2 lncRNA/BRG1/DLX1 interactions reveal RNA-dependent inhibition of chromatin remodeling., Development
- Carter (2015), Circulating long noncoding RNA GAS5 levels are correlated to prevalence of type 2 diabetes mellitus., BBA Clin
- Chen (2015), Predicting lncRNA-disease associations and constructing lncRNA functional similarity network based on the information of miRNA., Sci Rep
- Chen (2015), Up regulation of the long non-coding RNA NEAT1 promotes esophageal squamous cell carcinoma cell progression and correlates with poor prognosis., Am J Cancer Res
- Choudhry (2015), Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival., Oncogene
- Dobson (2015), A conserved charged single α-helix with a putative steric role in paraspeckle formation., RNA
- Elbarbary (2015), CARMing down the SINEs of anarchy: two paths to freedom from paraspeckle detention., Genes Dev.
- Giannakakis (2015), Contrasting expression patterns of coding and noncoding parts of the human genome upon oxidative stress., Sci Rep
- Guo (2015), Clinical implication of long non-coding RNA NEAT1 expression in hepatocellular carcinoma patients., Int J Clin Exp Pathol
- Hennig (2015), Prion-like domains in RNA binding proteins are essential for building subnuclear paraspeckles., J. Cell Biol.
- Hu (2015), A common set of distinct features that characterize noncoding RNAs across multiple species., Nucleic Acids Res.
- Hu (2015), Protein arginine methyltransferase CARM1 attenuates the paraspeckle-mediated nuclear retention of mRNAs containing IRAlus., Genes Dev.
- Imam (2015), The lncRNA NRON modulates HIV-1 replication in a NFAT-dependent manner and is differentially regulated by early and late viral proteins., Sci Rep
- Kawaguchi (2015), SWI/SNF chromatin-remodeling complexes function in noncoding RNA-dependent assembly of nuclear bodies., Proc. Natl. Acad. Sci. U.S.A.
- Kawaguchi (2015), Chromatin remodeling complexes in the assembly of long noncoding RNA-dependent nuclear bodies., Nucleus
- Lee (2015), The structure of human SFPQ reveals a coiled-coil mediated polymer essential for functional aggregation in gene regulation., Nucleic Acids Res.
- Li (2015), NEAT expression is associated with tumor recurrence and unfavorable prognosis in colorectal cancer., Oncotarget
- Liu (2015), Altered expression of long non-coding RNAs during genotoxic stress-induced cell death in human glioma cells., J. Neurooncol.
- Oliver (2015), Disruption of Visc-2, a Brain-Expressed Conserved Long Noncoding RNA, Does Not Elicit an Overt Anatomical or Behavioral Phenotype., Cereb. Cortex
- Pan (2015), Upregulation and clinicopathological significance of long non-coding NEAT1 RNA in NSCLC tissues., Asian Pac. J. Cancer Prev.
- Pastori (2015), The Bromodomain protein BRD4 controls HOTAIR, a long noncoding RNA essential for glioblastoma proliferation., Proc. Natl. Acad. Sci. U.S.A.
- Peng (2015), Long non-coding RNA MEG3 functions as a competing endogenous RNA to regulate gastric cancer progression., J. Exp. Clin. Cancer Res.
- Persson (2015), Transcriptome analysis of controlled and therapy-resistant childhood asthma reveals distinct gene expression profiles., J. Allergy Clin. Immunol.
- Quek (2015), lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs., Nucleic Acids Res.
- Rice (2015), Roles of microRNAs and long-noncoding RNAs in human immunodeficiency virus replication., Wiley Interdiscip Rev RNA
- Ryan (2015), Transcriptomic signatures in whole blood of patients who acquire a chronic inflammatory response syndrome (CIRS) following an exposure to the marine toxin ciguatoxin., BMC Med Genomics
- Shen (2015), Exploration of Deregulated Long Non-Coding RNAs in Association with Hepatocarcinogenesis and Survival., Cancers (Basel)
- Szczepińska (2015), DIS3 shapes the RNA polymerase II transcriptome in humans by degrading a variety of unwanted transcripts., Genome Res.
- Sørensen (2015), Long non-coding RNA expression profiles predict metastasis in lymph node-negative breast cancer independently of traditional prognostic markers., Breast Cancer Res.
- Wang (2015), Identification of lncRNA-associated competing triplets reveals global patterns and prognostic markers for cancer., Nucleic Acids Res.
- Wang (2015), Serum LncRNAs Profiles Serve as Novel Potential Biomarkers for the Diagnosis of HBV-Positive Hepatocellular Carcinoma., PLoS ONE
- Xiao (2015), Predicting the functions of long noncoding RNAs using RNA-seq based on Bayesian network., Biomed Res Int
- Yamazaki (2015), The building process of the functional paraspeckle with long non-coding RNAs., Front Biosci (Elite Ed)
- Yin (2015), SnoVectors for nuclear expression of RNA., Nucleic Acids Res.
- Atianand (2014), Long non-coding RNAs and control of gene expression in the immune system., Trends Mol Med
- Chakravarty (2014), The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer., Nat Commun
- Cooper (2014), Long Non-Coding RNA NEAT1 Associates with SRp40 to Temporally Regulate PPARγ2 Splicing during Adipogenesis in 3T3-L1 Cells., Genes (Basel)
- Gremlich (2014), The long non-coding RNA NEAT1 is increased in IUGR placentas, leading to potential new hypotheses of IUGR origin/development., Placenta
- Guallar (2014), RNA-binding proteins in pluripotency, differentiation, and reprogramming., Front Biol (Beijing)
- Hirose (2014), NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies., Mol. Biol. Cell
- Huang (2014), Urinary Xist is a potential biomarker for membranous nephropathy., Biochem. Biophys. Res. Commun.
- Ishizuka (2014), Formation of nuclear bodies by the lncRNA Gomafu-associating proteins Celf3 and SF1., Genes Cells
- Kambara (2014), Negative regulation of the interferon response by an interferon-induced long non-coding RNA., Nucleic Acids Res.
- Li (2014), Decoding the noncoding: prospective of lncRNA-mediated innate immune regulation., RNA Biol
- Li (2014), Discovery of Protein-lncRNA Interactions by Integrating Large-Scale CLIP-Seq and RNA-Seq Datasets., Front Bioeng Biotechnol
- Marques Howarth (2014), Long noncoding RNA EWSAT1-mediated gene repression facilitates Ewing sarcoma oncogenesis., J. Clin. Invest.
- Park (2014), lncRNAtor: a comprehensive resource for functional investigation of long non-coding RNAs., Bioinformatics
- Schmid (2014), SnapShot: nuclear RNAPII transcript modification., Cell
- Shelkovnikova (2014), Compromised paraspeckle formation as a pathogenic factor in FUSopathies., Hum. Mol. Genet.
- Shen (2014), Phosphorothioate oligonucleotides can displace NEAT1 RNA and form nuclear paraspeckle-like structures., Nucleic Acids Res.
- Shichino (2014), Meiotic long non-coding meiRNA accumulates as a dot at its genetic locus facilitated by Mmi1 and plays as a decoy to lure Mmi1., Open Biol
- Standaert (2014), The long noncoding RNA Neat1 is required for mammary gland development and lactation., RNA
- Su (2014), Comprehensive analysis of long non-coding RNAs in human breast cancer clinical subtypes., Oncotarget
- Takahashi (2014), Extracellular vesicle-mediated transfer of long non-coding RNA ROR modulates chemosensitivity in human hepatocellular cancer., FEBS Open Bio
- Takahashi (2014), Widespread genome transcription: new possibilities for RNA therapies., Biochem. Biophys. Res. Commun.
- West (2014), The long noncoding RNAs NEAT1 and MALAT1 bind active chromatin sites., Mol. Cell
- Xu (2014), Long non-coding RNA LSINCT5 predicts negative prognosis and exhibits oncogenic activity in gastric cancer., Medicine (Baltimore)
- Yoon (2014), PAR-CLIP analysis uncovers AUF1 impact on target RNA fate and genome integrity., Nat Commun
- You (2014), MicroRNA-449a inhibits cell growth in lung cancer and regulates long noncoding RNA nuclear enriched abundant transcript 1., Indian J Cancer
- Zeng (2014), Inhibition of long non-coding RNA NEAT1 impairs myeloid differentiation in acute promyelocytic leukemia cells., BMC Cancer
- Zhao (2014), Role of HOTAIR long noncoding RNA in metastatic progression of lung cancer., Eur Rev Med Pharmacol Sci
- Bavarva (2013), Characterizing the Genetic Basis for Nicotine Induced Cancer Development: A Transcriptome Sequencing Study., PLoS ONE
- Chen (2013), Novel human lncRNA-disease association inference based on lncRNA expression profiles., Bioinformatics
- Dodd (2013), Digital quantitation of potential therapeutic target RNAs., Nucleic Acid Ther
- Du (2013), Integrative genomic analyses reveal clinically relevant long noncoding RNAs in human cancer., Nat. Struct. Mol. Biol.
- Guan (2013), Switching cell fate, ncRNAs coming to play., Cell Death Dis
- Hangauer (2013), Pervasive transcription of the human genome produces thousands of previously unidentified long intergenic noncoding RNAs., PLoS Genet.
- Kapusta (2013), Transposable elements are major contributors to the origin, diversification, and regulation of vertebrate long noncoding RNAs., PLoS Genet.
- Naganuma (2013), Paraspeckle formation during the biogenesis of long non-coding RNAs., RNA Biol
- Nishimoto (2013), The long non-coding RNA nuclear-enriched abundant transcript 1_2 induces paraspeckle formation in the motor neuron during the early phase of amyotrophic lateral sclerosis., Mol Brain
- Tang (2013), Long noncoding RNA HOTAIR is associated with motility, invasion, and metastatic potential of metastatic melanoma., Biomed Res Int
- Wan (2013), Long non-coding RNA ANRIL (CDKN2B-AS) is induced by the ATM-E2F1 signaling pathway., Cell. Signal.
- Zhang (2013), NEAT1 long noncoding RNA and paraspeckle bodies modulate HIV-1 posttranscriptional expression., MBio
- Clark (2012), Genome-wide analysis of long noncoding RNA stability., Genome Res.
- Hirose (2012), Paraspeckles: possible nuclear hubs by the RNA for the RNA., Biomol Concepts
- Ip (2012), Long non-coding RNAs in nuclear bodies., Dev. Growth Differ.
- Johnson (2012), Long non-coding RNAs in Huntington's disease neurodegeneration., Neurobiol. Dis.
- Lipovich (2012), Activity-dependent human brain coding/noncoding gene regulatory networks., Genetics
- Miyagawa (2012), Identification of cis- and trans-acting factors involved in the localization of MALAT-1 noncoding RNA to nuclear speckles., RNA
- Mizutani (2012), Identification and characterization of novel genotoxic stress-inducible nuclear long noncoding RNAs in mammalian cells., PLoS ONE
- Naganuma (2012), Alternative 3'-end processing of long noncoding RNA initiates construction of nuclear paraspeckles., EMBO J.
- Nakagawa (2012), Malat1 is not an essential component of nuclear speckles in mice., RNA
- Passon (2012), Structure of the heterodimer of human NONO and paraspeckle protein component 1 and analysis of its role in subnuclear body formation., Proc. Natl. Acad. Sci. U.S.A.
- Qureshi (2012), Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease., Nat. Rev. Neurosci.
- Schor (2012), Perturbation of chromatin structure globally affects localization and recruitment of splicing factors., PLoS ONE
- Yin (2012), Long noncoding RNAs with snoRNA ends., Mol. Cell
- Guttman (2011), lincRNAs act in the circuitry controlling pluripotency and differentiation., Nature
- Mao (2011), Direct visualization of the co-transcriptional assembly of a nuclear body by noncoding RNAs., Nat. Cell Biol.
- Michelhaugh (2011), Mining Affymetrix microarray data for long non-coding RNAs: altered expression in the nucleus accumbens of heroin abusers., J. Neurochem.
- Nakagawa (2011), eXIST with matrix-associated proteins., Trends Cell Biol.
- Nakagawa (2011), Paraspeckles are subpopulation-specific nuclear bodies that are not essential in mice., J. Cell Biol.
- Shevtsov (2011), Nucleation of nuclear bodies by RNA., Nat. Cell Biol.
- Silva (2011), LSINCT5 is over expressed in breast and ovarian cancer and affects cellular proliferation., RNA Biol
- Simon (2011), The genomic binding sites of a noncoding RNA., Proc. Natl. Acad. Sci. U.S.A.
- Tollervey (2011), Characterizing the RNA targets and position-dependent splicing regulation by TDP-43., Nat. Neurosci.
- Yang (2011), Genomewide characterization of non-polyadenylated RNAs., Genome Biol.
- Zong (2011), RNA splicing control: yet another gene regulatory role for long nuclear noncoding RNAs., RNA Biol
- Mercer (2010), Long noncoding RNAs in neuronal-glial fate specification and oligodendrocyte lineage maturation., BMC Neurosci
- Murthy (2010), Identification of protein interaction regions of VINC/NEAT1/Men epsilon RNA., FEBS Lett.
- Souquere (2010), Highly ordered spatial organization of the structural long noncoding NEAT1 RNAs within paraspeckle nuclear bodies., Mol. Biol. Cell
- Chen (2009), Altered nuclear retention of mRNAs containing inverted repeats in human embryonic stem cells: functional role of a nuclear noncoding RNA., Mol. Cell
- Clemson (2009), An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles., Mol. Cell
- Friedel (2009), Conserved principles of mammalian transcriptional regulation revealed by RNA half-life., Nucleic Acids Res.
- Sasaki (2009), MENepsilon/beta noncoding RNAs are essential for structural integrity of nuclear paraspeckles., Proc. Natl. Acad. Sci. U.S.A.
- Sunwoo (2009), MEN epsilon/beta nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of paraspeckles., Genome Res.
- Hutchinson (2007), A screen for nuclear transcripts identifies two linked noncoding RNAs associated with SC35 splicing domains., BMC Genomics
- Saha (2006), Identification and characterization of a virus-inducible non-coding RNA in mouse brain., J. Gen. Virol.
- Geirsson (2003), Human trophoblast noncoding RNA suppresses CIITA promoter III activity in murine B-lymphocytes., Biochem. Biophys. Res. Commun.
- Peyman (1999), Repression of major histocompatibility complex genes by a human trophoblast ribonucleic acid., Biol. Reprod.
- Guru (1997), A transcript map for the 2.8-Mb region containing the multiple endocrine neoplasia type 1 locus., Genome Res.
LNCipedia transcript ID history
LNCipedia version | LNCipedia transcript ID |
---|---|
3.1 | lnc-AP000769.1-2:6 |
4.0 | NEAT1:2 |
4.1 | NEAT1:2 |
5.0 | NEAT1:2 |
5.1 | NEAT1:2 |
5.2 | NEAT1:2 |