Transcript: PCGEM1:6

Basic information

LNCipedia transcript ID: PCGEM1:6 
LNCipedia gene ID: PCGEM1
Location (hg38): chr2:192749845-192776899
Strand: +
Class: intergenic
Sequence Ontology term: lincRNA
Transcript size: 1590 bp
Exons: 3
Sources: Ensembl release 87 - Dec 2016
Alternative transcript names: ENST00000454040.5
Alternative gene names: ENSG00000227418.6; PCGEM1; NCRNA00071; LINC00071; PCAT9


RNA sequence:

Structure:

Protein coding potential

Metric Raw result Interpretation
PRIDE reprocessing 2.0 0 non-coding 
Lee translation initiation sites non-coding 
PhyloCSF score -132.1042 non-coding 
CPAT coding probability 0.04% non-coding 
Bazzini small ORFs 0 non-coding 

In stringent set: yes

Locus conservation

Locus conservation?
PCGEM1:6 no no no no

Available literature

  1. Kang (2016), PCGEM1 stimulates proliferation of osteoarthritic synoviocytes by acting as a sponge for miR-770., J. Orthop. Res.
  2. Du (2015), The association analysis of lncRNA HOTAIR genetic variants and gastric cancer risk in a Chinese population., Oncotarget
  3. Hu (2015), Downregulation of NUF2 inhibits tumor growth and induces apoptosis by regulating lncRNA AF339813., Int J Clin Exp Pathol
  4. Parolia (2015), The long non-coding RNA PCGEM1 is regulated by androgen receptor activity in vivo., Mol. Cancer
  5. Shih (2015), Non-Coding RNAs in Castration-Resistant Prostate Cancer: Regulation of Androgen Receptor Signaling and Cancer Metabolism., Int J Mol Sci
  6. Tantai (2015), Combined identification of long non-coding RNA XIST and HIF1A-AS1 in serum as an effective screening for non-small cell lung cancer., Int J Clin Exp Pathol
  7. Wang (2015), Upregulated lncRNA-UCA1 contributes to progression of lung cancer and is closely related to clinical diagnosis as a predictive biomarker in plasma., Int J Clin Exp Med
  8. Hung (2014), A long noncoding RNA connects c-Myc to tumor metabolism., Proc. Natl. Acad. Sci. U.S.A.
  9. Pestell (2014), Long and noncoding RNAs (lnc-RNAs) determine androgen receptor dependent gene expression in prostate cancer growth in vivo., Asian J. Androl.
  10. Petrovics (2014), Long noncoding RNA-mediated activation of androgen receptor in prostate cancer., Asian J. Androl.
  11. Prensner (2014), The IncRNAs PCGEM1 and PRNCR1 are not implicated in castration resistant prostate cancer., Oncotarget
  12. Walsh (2014), Long noncoding RNAs and prostate carcinogenesis: the missing 'linc'?, Trends Mol Med
  13. Du (2013), Integrative genomic analyses reveal clinically relevant long noncoding RNAs in human cancer., Nat. Struct. Mol. Biol.
  14. Wu (2013), Hypomethylation of noncoding DNA regions and overexpression of the long noncoding RNA, AFAP1-AS1, in Barrett's esophagus and esophageal adenocarcinoma., Gastroenterology
  15. Xue (2013), Association between lncrna PCGEM1 polymorphisms and prostate cancer risk., Prostate Cancer Prostatic Dis.
  16. Yang (2013), lncRNA-dependent mechanisms of androgen-receptor-regulated gene activation programs., Nature
  17. Ren (2012), RNA-seq analysis of prostate cancer in the Chinese population identifies recurrent gene fusions, cancer-associated long noncoding RNAs and aberrant alternative splicings., Cell Res.
  18. Ifere (2009), Differential effects of cholesterol and phytosterols on cell proliferation, apoptosis and expression of a prostate specific gene in prostate cancer cell lines., Cancer Detect. Prev.
  19. Fu (2006), Regulation of apoptosis by a prostate-specific and prostate cancer-associated noncoding gene, PCGEM1., DNA Cell Biol.
  20. Petrovics (2004), Elevated expression of PCGEM1, a prostate-specific gene with cell growth-promoting function, is associated with high-risk prostate cancer patients., Oncogene
  21. Srikantan (2000), PCGEM1, a prostate-specific gene, is overexpressed in prostate cancer., Proc. Natl. Acad. Sci. U.S.A.


LNCipedia transcript ID history

LNCipedia version LNCipedia transcript ID
4.1 PCGEM1:6
5.0 PCGEM1:6
5.1 PCGEM1:6
5.2 PCGEM1:6