Transcript: XIST:48

Basic information

LNCipedia transcript ID: XIST:48 
LNCipedia gene ID: XIST
Location (hg38): chrX:73820614-73849001
Strand: -
Class: intergenic
Sequence Ontology term: lincRNA
Transcript size: 10417 bp
Exons: 7
Sources: FANTOM CAT (stringent)
Alternative transcript names: ENSG00000229807.5|HBMT00001549401.1
Alternative gene names: NCRNA00001; DXS1089; swd66; LINC00001

RNA sequence:


Protein coding potential

Metric Raw result Interpretation
PRIDE reprocessing 2.0 0 non-coding 
Lee translation initiation sites non-coding 
PhyloCSF score -17.5471 non-coding 
CPAT coding probability 4.52% non-coding 
Bazzini small ORFs 0 non-coding 

In stringent set: yes

Locus conservation

Locus conservation?
XIST:48 no no no no

Available literature

  1. Briese (2016), Whole transcriptome profiling reveals the RNA content of motor axons., Nucleic Acids Res.
  2. Dixon-McDougall (2016), The making of a Barr body: the mosaic of factors that eXIST on the mammalian inactive X chromosome., Biochem. Cell Biol.
  3. Richard (2016), Understanding the Complex Circuitry of lncRNAs at the X-inactivation Center and Its Implications in Disease Conditions., Curr. Top. Microbiol. Immunol.
  4. Sun (2016), Involvement of lncRNA dysregulation in gastric cancer., Histol. Histopathol.
  5. Xie (2016), Long non-coding RNAs in colorectal cancer., Oncotarget
  6. Yue (2016), Dynamic interplay and function of multiple noncoding genes governing X chromosome inactivation., Biochim. Biophys. Acta
  7. Briggs (2015), Single-Cell XIST Expression in Human Preimplantation Embryos and Newly Reprogrammed Female Induced Pluripotent Stem Cells., Stem Cells
  8. Cabili (2015), Localization and abundance analysis of human lncRNAs at single-cell and single-molecule resolution., Genome Biol.
  9. Cajigas (2015), Evf2 lncRNA/BRG1/DLX1 interactions reveal RNA-dependent inhibition of chromatin remodeling., Development
  10. Cerase (2015), Xist localization and function: new insights from multiple levels., Genome Biol.
  11. Chacko (2015), The lncRNA RZE1 Controls Cryptococcal Morphological Transition., PLoS Genet.
  12. Chen (2015), Differential lncRNA expression profiles in recurrent gliomas compared with primary gliomas identified by microarray analysis., Int J Clin Exp Med
  13. Chen (2015), Predicting lncRNA-disease associations and constructing lncRNA functional similarity network based on the information of miRNA., Sci Rep
  14. Ching (2015), Non-coding yet non-trivial: a review on the computational genomics of lincRNAs., BioData Min
  15. Chu (2015), Systematic discovery of Xist RNA binding proteins., Cell
  16. Fang (2015), Probing Xist RNA Structure in Cells Using Targeted Structure-Seq., PLoS Genet.
  17. Fiedler (2015), Development of Long Noncoding RNA-Based Strategies to Modulate Tissue Vascularization., J. Am. Coll. Cardiol.
  18. Galupa (2015), X-chromosome inactivation: new insights into cis and trans regulation., Curr. Opin. Genet. Dev.
  19. Guo (2015), Biological significance of long non-coding RNA FTX expression in human colorectal cancer., Int J Clin Exp Med
  20. Hu (2015), NBAT1 suppresses breast cancer metastasis by regulating DKK1 via PRC2., Oncotarget
  21. Jiao (2015), Long intergenic non-coding RNA induced by X-ray irradiation regulates DNA damage response signaling in the human bronchial epithelial BEAS-2B cell line., Oncol Lett
  22. Kelsey (2015), Impact of flanking chromosomal sequences on localization and silencing by the human non-coding RNA XIST., Genome Biol.
  23. Kota (2015), Uncoupling of X-linked gene silencing from XIST binding by DICER1 and chromatin modulation on human inactive X chromosome., Chromosoma
  24. Lalevée (2015), Long noncoding RNAs in human disease: emerging mechanisms and therapeutic strategies., Epigenomics
  25. Li (2015), LncRNA ontology: inferring lncRNA functions based on chromatin states and expression patterns., Oncotarget
  26. Lorenzen (2015), Circulating long noncoding RNATapSaki is a predictor of mortality in critically ill patients with acute kidney injury., Clin. Chem.
  27. Mao (2015), Oxamflatin treatment enhances cloned porcine embryo development and nuclear reprogramming., Cell Reprogram
  28. Minajigi (2015), Chromosomes. A comprehensive Xist interactome reveals cohesin repulsion and an RNA-directed chromosome conformation., Science
  29. Na (2015), Long non-coding RNA UCA1 contributes to the progression of prostate cancer and regulates proliferation through KLF4-KRT6/13 signaling pathway., Int J Clin Exp Med
  30. Nwigwe (2015), Boundary Associated Long Noncoding RNA Mediates Long-Range Chromosomal Interactions., PLoS ONE
  31. Peffers (2015), Transcriptome analysis of ageing in uninjured human Achilles tendon., Arthritis Res. Ther.
  32. Pei (2015), Notch-1 promotes breast cancer cells proliferation by regulating LncRNA GAS5., Int J Clin Exp Med
  33. Peng (2015), Epigenetic regulation of drug metabolism and transport., Acta Pharm Sin B
  34. Qi (2015), X chromosome inactivation in human parthenogenetic embryonic stem cells following prolonged passaging., Int. J. Mol. Med.
  35. Quek (2015), lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs., Nucleic Acids Res.
  36. Rupaimoole (2015), Long Noncoding RNA Ceruloplasmin Promotes Cancer Growth by Altering Glycolysis., Cell Rep
  37. Sarkar (2015), An Xist-activating antisense RNA required for X-chromosome inactivation., Nat Commun
  38. Scarola (2015), Epigenetic silencing of Oct4 by a complex containing SUV39H1 and Oct4 pseudogene lncRNA., Nat Commun
  39. Shang (2015), A global view of network of lncRNAs and their binding proteins., Mol Biosyst
  40. Shen (2015), Prognostic and predictive values of long non-coding RNA LINC00472 in breast cancer., Oncotarget
  41. Smolle (2015), Long Non-Coding RNAs in Endometrial Carcinoma., Int J Mol Sci
  42. Sun (2015), Chromosome X genomic and epigenomic aberrations and clinical implications in breast cancer by base resolution profiling., Epigenomics
  43. Tantai (2015), Combined identification of long non-coding RNA XIST and HIF1A-AS1 in serum as an effective screening for non-small cell lung cancer., Int J Clin Exp Pathol
  44. Wang (2015), Identification of lncRNA-associated competing triplets reveals global patterns and prognostic markers for cancer., Nucleic Acids Res.
  45. Wang (2015), Long noncoding RNA derived from CD244 signaling epigenetically controls CD8+ T-cell immune responses in tuberculosis infection., Proc. Natl. Acad. Sci. U.S.A.
  46. Wang (2015), Upregulated lncRNA-UCA1 contributes to progression of lung cancer and is closely related to clinical diagnosis as a predictive biomarker in plasma., Int J Clin Exp Med
  47. Wang (2015), Serum LncRNAs Profiles Serve as Novel Potential Biomarkers for the Diagnosis of HBV-Positive Hepatocellular Carcinoma., PLoS ONE
  48. Werner (2015), Nuclear Fractionation Reveals Thousands of Chromatin-Tethered Noncoding RNAs Adjacent to Active Genes., Cell Rep
  49. Wongtrakoongate (2015), Association of the Long Non-coding RNA Steroid Receptor RNA Activator (SRA) with TrxG and PRC2 Complexes., PLoS Genet.
  50. Wu (2015), The long non-coding RNA HNF1A-AS1 regulates proliferation and metastasis in lung adenocarcinoma., Oncotarget
  51. Wu (2015), The converging roles of BRD4 and gene transcription in pluripotency and oncogenesis., RNA Dis
  52. Xiao (2015), Long Noncoding RNA ADINR Regulates Adipogenesis by Transcriptionally Activating C/EBPα., Stem Cell Reports
  53. Xu (2015), A transposable element within the Non-canonical telomerase RNA of Arabidopsis thaliana modulates telomerase in response to DNA damage [corrected]., PLoS Genet.
  54. Yang (2015), The lncRNA Firre anchors the inactive X chromosome to the nucleolus by binding CTCF and maintains H3K27me3 methylation., Genome Biol.
  55. Yao (2015), Knockdown of long non-coding RNA XIST exerts tumor-suppressive functions in human glioblastoma stem cells by up-regulating miR-152., Cancer Lett.
  56. Zhang (2015), Long Noncoding RNA Expression Signatures of Metastatic Nasopharyngeal Carcinoma and Their Prognostic Value., Biomed Res Int
  57. Zlotorynski (2015), Non-coding RNA: X-chromosome inactivation unravelled., Nat. Rev. Mol. Cell Biol.
  58. Alaimo (2014), ncPred: ncRNA-Disease Association Prediction through Tripartite Network-Based Inference., Front Bioeng Biotechnol
  59. Alam (2014), Promoter analysis reveals globally differential regulation of human long non-coding RNA and protein-coding genes., PLoS ONE
  60. Almlöf (2014), Single nucleotide polymorphisms with cis-regulatory effects on long non-coding transcripts in human primary monocytes., PLoS ONE
  61. Basu (2014), Using amino-labeled nucleotide probes for simultaneous single molecule RNA-DNA FISH., PLoS ONE
  62. Bhatnagar (2014), Genetic and pharmacological reactivation of the mammalian inactive X chromosome., Proc. Natl. Acad. Sci. U.S.A.
  63. Chakraborty (2014), The predictive power of synthetic nucleic acid technologies in RNA biology., Acc. Chem. Res.
  64. Chapman (2014), Differentially methylated CpG island within human XIST mediates alternative P2 transcription and YY1 binding., BMC Genet.
  65. Cifuentes-Rojas (2014), Regulatory interactions between RNA and polycomb repressive complex 2., Mol. Cell
  66. Cooper (2014), Long Non-Coding RNA NEAT1 Associates with SRp40 to Temporally Regulate PPARγ2 Splicing during Adipogenesis in 3T3-L1 Cells., Genes (Basel)
  67. Ding (2014), Long intergenic non-coding RNAs (LincRNAs) identified by RNA-seq in breast cancer., PLoS ONE
  68. Feinberg (2014), The nucleolus gets the silent treatment., Cell Stem Cell
  69. Feng (2014), Methods for the study of long noncoding RNA in cancer cell signaling., Methods Mol. Biol.
  70. Figueiredo (2014), Non-coding roX RNAs prevent the binding of the MSL-complex to heterochromatic regions., PLoS Genet.
  71. Gendrel (2014), Noncoding RNAs and epigenetic mechanisms during X-chromosome inactivation., Annu. Rev. Cell Dev. Biol.
  72. Giorgetti (2014), Predictive polymer modeling reveals coupled fluctuations in chromosome conformation and transcription., Cell
  73. Guallar (2014), RNA-binding proteins in pluripotency, differentiation, and reprogramming., Front Biol (Beijing)
  74. Ha (2014), A comprehensive analysis of piRNAs from adult human testis and their relationship with genes and mobile elements., BMC Genomics
  75. Hacisuleyman (2014), Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre., Nat. Struct. Mol. Biol.
  76. Hu (2014), A functional genomic approach identifies FAL1 as an oncogenic long noncoding RNA that associates with BMI1 and represses p21 expression in cancer., Cancer Cell
  77. Huang (2014), Urinary Xist is a potential biomarker for membranous nephropathy., Biochem. Biophys. Res. Commun.
  78. Ishizuka (2014), Formation of nuclear bodies by the lncRNA Gomafu-associating proteins Celf3 and SF1., Genes Cells
  79. Jiang (2014), Xist deficiency and disorders of X-inactivation in rabbit embryonic stem cells can be rescued by transcription-factor-mediated conversion., Stem Cells Dev.
  80. Li (2014), starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein-RNA interaction networks from large-scale CLIP-Seq data., Nucleic Acids Res.
  81. Li (2014), A polymorphism rs12325489C>T in the lincRNA-ENST00000515084 exon was found to modulate breast cancer risk via GWAS-based association analyses., PLoS ONE
  82. Li (2014), Comparison of long non‑coding RNAs, microRNAs and messenger RNAs involved in initiation and progression of esophageal squamous cell carcinoma., Mol Med Rep
  83. Liu (2014), LncRNAs expression signatures of hepatocellular carcinoma revealed by microarray., World J. Gastroenterol.
  84. Luo (2014), High-resolution chromosomal microarray analysis of early-stage human embryonic stem cells reveals an association between X chromosome instability and skewed X inactivation., Cell Biosci
  85. Makhlouf (2014), A prominent and conserved role for YY1 in Xist transcriptional activation., Nat Commun
  86. Marques Howarth (2014), Long noncoding RNA EWSAT1-mediated gene repression facilitates Ewing sarcoma oncogenesis., J. Clin. Invest.
  87. Mathiyalagan (2014), Interplay of chromatin modifications and non-coding RNAs in the heart., Epigenetics
  88. McKiernan (2014), Long noncoding RNA are aberrantly expressed in vivo in the cystic fibrosis bronchial epithelium., Int. J. Biochem. Cell Biol.
  89. Minkovsky (2014), The Mbd1-Atf7ip-Setdb1 pathway contributes to the maintenance of X chromosome inactivation., Epigenetics Chromatin
  90. Negishi (2014), A new lncRNA, APTR, associates with and represses the CDKN1A/p21 promoter by recruiting polycomb proteins., PLoS ONE
  91. Nielsen (2014), Identification of expressed and conserved human noncoding RNAs., RNA
  92. Olivier-Van Stichelen (2014), X-inactivation normalizes O-GlcNAc transferase levels and generates an O-GlcNAc-depleted Barr body., Front Genet
  93. Pasque (2014), X chromosome reactivation dynamics reveal stages of reprogramming to pluripotency., Cell
  94. Payer (2014), Coupling of X-chromosome reactivation with the pluripotent stem cell state., RNA Biol
  95. Pestell (2014), Long and noncoding RNAs (lnc-RNAs) determine androgen receptor dependent gene expression in prostate cancer growth in vivo., Asian J. Androl.
  96. Pircher (2014), Ribosome-associated ncRNAs: an emerging class of translation regulators., RNA Biol
  97. Porro (2014), TERRA-reinforced association of LSD1 with MRE11 promotes processing of uncapped telomeres., Cell Rep
  98. Prensner (2014), The long non-coding RNA PCAT-1 promotes prostate cancer cell proliferation through cMyc., Neoplasia
  99. Quagliata (2014), Long noncoding RNA HOTTIP/HOXA13 expression is associated with disease progression and predicts outcome in hepatocellular carcinoma patients., Hepatology
  100. Quinn (2014), Revealing long noncoding RNA architecture and functions using domain-specific chromatin isolation by RNA purification., Nat. Biotechnol.
  101. Quinodoz (2014), Long noncoding RNAs: an emerging link between gene regulation and nuclear organization., Trends Cell Biol.
  102. Rajpathak (2014), Human 45,X fibroblast transcriptome reveals distinct differentially expressed genes including long noncoding RNAs potentially associated with the pathophysiology of Turner syndrome., PLoS ONE
  103. Rinn (2014), RNA Function. RNA and dynamic nuclear organization., Science
  104. Sarma (2014), ATRX directs binding of PRC2 to Xist RNA and Polycomb targets., Cell
  105. Shichino (2014), Meiotic long non-coding meiRNA accumulates as a dot at its genetic locus facilitated by Mmi1 and plays as a decoy to lure Mmi1., Open Biol
  106. Soma (2014), Ftx is dispensable for imprinted X-chromosome inactivation in preimplantation mouse embryos., Sci Rep
  107. Song (2014), A long non-coding RNA, GAS5, plays a critical role in the regulation of miR-21 during osteoarthritis., J. Orthop. Res.
  108. Su (2014), Comprehensive analysis of long non-coding RNAs in human breast cancer clinical subtypes., Oncotarget
  109. Sultan (2014), Influence of RNA extraction methods and library selection schemes on RNA-seq data., BMC Genomics
  110. Sun (2014), A novel antisense long noncoding RNA within the IGF1R gene locus is imprinted in hematopoietic malignancies., Nucleic Acids Res.
  111. Wang (2014), The long noncoding RNA CHRF regulates cardiac hypertrophy by targeting miR-489., Circ. Res.
  112. Yang (2014), A network based method for analysis of lncRNA-disease associations and prediction of lncRNAs implicated in diseases., PLoS ONE
  113. Yoon (2014), PAR-CLIP analysis uncovers AUF1 impact on target RNA fate and genome integrity., Nat Commun
  114. Yue (2014), Quick fluorescent in situ hybridization protocol for Xist RNA combined with immunofluorescence of histone modification in X-chromosome inactivation., J Vis Exp
  115. Zhang (2014), Comparative DNA methylome analysis of endometrial carcinoma reveals complex and distinct deregulation of cancer promoters and enhancers., BMC Genomics
  116. Zhao (2014), Comprehensive characterization of cancer subtype associated long non-coding RNAs and their clinical implications., Sci Rep
  117. de Oliveira Georges (2014), Aberrant patterns of X chromosome inactivation in a new line of human embryonic stem cells established in physiological oxygen concentrations., Stem Cell Rev
  118. Agostini (2013), X-inactivation: quantitative predictions of protein interactions in the Xist network., Nucleic Acids Res.
  119. Akbari (2013), Transcriptome profiling of Nasonia vitripennis testis reveals novel transcripts expressed from the selfish B chromosome, paternal sex ratio., G3 (Bethesda)
  120. Alaei-Mahabadi (2013), Limited evidence for evolutionarily conserved targeting of long non-coding RNAs by microRNAs., Silence
  121. Amort (2013), Long non-coding RNAs as targets for cytosine methylation., RNA Biol
  122. Batista (2013), Long noncoding RNAs: cellular address codes in development and disease., Cell
  123. Beato (2013), A new role for an old player: steroid receptor RNA Activator (SRA) represses hormone inducible genes., Transcription
  124. Bhan (2013), Antisense transcript long noncoding RNA (lncRNA) HOTAIR is transcriptionally induced by estradiol., J. Mol. Biol.
  125. Bhartiya (2013), lncRNome: a comprehensive knowledgebase of human long noncoding RNAs., Database (Oxford)
  126. Bhattacharjee (2013), Combinatorial control of gene expression., Biomed Res Int
  127. Bischoff (2013), Differences in X-chromosome transcriptional activity and cholesterol metabolism between placentae from swine breeds from Asian and Western origins., PLoS ONE
  128. Bolisetty (2013), Circuitous route to transcription regulation., Mol. Cell
  129. Chadwick (2013), Molecular versatility: the many faces and functions of noncoding RNA., Chromosome Res.
  130. Dasen (2013), Long noncoding RNAs in development: solidifying the Lncs to Hox gene regulation., Cell Rep
  131. Dimond (2013), Molecular biology. Long noncoding RNAs Xist in three dimensions., Science
  132. Disteche (2013), How to correct chromosomal trisomy., Cell Res.
  133. Donley (2013), Asynchronous replication, mono-allelic expression, and long range Cis-effects of ASAR6., PLoS Genet.
  134. Fan (2013), A long non-coding RNA, PTCSC3, as a tumor suppressor and a target of miRNAs in thyroid cancer cells., Exp Ther Med
  135. Guan (2013), Switching cell fate, ncRNAs coming to play., Cell Death Dis
  136. Hangauer (2013), Pervasive transcription of the human genome produces thousands of previously unidentified long intergenic noncoding RNAs., PLoS Genet.
  137. He (2013), ANRIL/CDKN2B-AS shows two-stage clade-specific evolution and becomes conserved after transposon insertions in simians., BMC Evol. Biol.
  138. Jalali (2013), Systematic transcriptome wide analysis of lncRNA-miRNA interactions., PLoS ONE
  139. Jiang (2013), Translating dosage compensation to trisomy 21., Nature
  140. Juan (2013), Potential roles of microRNAs in regulating long intergenic noncoding RNAs., BMC Med Genomics
  141. Kapusta (2013), Transposable elements are major contributors to the origin, diversification, and regulation of vertebrate long noncoding RNAs., PLoS Genet.
  142. Kogure (2013), Extracellular Vesicle-Mediated Transfer of a Novel Long Noncoding RNA TUC339: A Mechanism of Intercellular Signaling in Human Hepatocellular Cancer., Genes Cancer
  143. Kung (2013), RNA in the loop., Dev. Cell
  144. Lai (2013), Activating RNAs associate with Mediator to enhance chromatin architecture and transcription., Nature
  145. Lawrence (2013), Interview: from Down's syndrome to basic epigenetics and back again., Epigenomics
  146. Li (2013), Targeted disruption of Hotair leads to homeotic transformation and gene derepression., Cell Rep
  147. Liu (2013), Identification of differentially expressed long non-coding RNAs in human ovarian cancer cells with different metastatic potentials., Cancer Biol Med
  148. Lu (2013), Genome-wide survey by ChIP-seq reveals YY1 regulation of lincRNAs in skeletal myogenesis., EMBO J.
  149. Luco (2013), The non-coding genome: a universe in expansion for fine-tuning the coding world., Genome Biol.
  150. Maclary (2013), Long nonoding RNAs in the X-inactivation center., Chromosome Res.
  151. Maenner (2013), ATP-dependent roX RNA remodeling by the helicase maleless enables specific association of MSL proteins., Mol. Cell
  152. McGraw (2013), Loss of DNMT1o disrupts imprinted X chromosome inactivation and accentuates placental defects in females., PLoS Genet.
  153. Minks (2013), XIST-induced silencing of flanking genes is achieved by additive action of repeat a monomers in human somatic cells., Epigenetics Chromatin
  154. Papait (2013), Long noncoding RNA: a new player of heart failure?, J Cardiovasc Transl Res
  155. Sado (2013), Advances in understanding chromosome silencing by the long non-coding RNA Xist., Philos. Trans. R. Soc. Lond., B, Biol. Sci.
  156. Salvador (2013), The histone deacetylase inhibitor abexinostat induces cancer stem cells differentiation in breast cancer with low Xist expression., Clin. Cancer Res.
  157. Santoro (2013), Silencing by the imprinted Airn macro lncRNA: transcription is the answer., Cell Cycle
  158. Sheffield (2013), Patterns of regulatory activity across diverse human cell types predict tissue identity, transcription factor binding, and long-range interactions., Genome Res.
  159. Simon (2013), High-resolution Xist binding maps reveal two-step spreading during X-chromosome inactivation., Nature
  160. Szafranski (2013), Small noncoding differentially methylated copy-number variants, including lncRNA genes, cause a lethal lung developmental disorder., Genome Res.
  161. Vallot (2013), XACT, a long noncoding transcript coating the active X chromosome in human pluripotent cells., Nat. Genet.
  162. Vallot (2013), [X chromosome inactivation in human: XACT and XIST, a non coding RNA for each X]., Med Sci (Paris)
  163. Vallot (2013), Long non-coding RNAs and human X-chromosome regulation: a coat for the active X chromosome., RNA Biol
  164. Volders (2013), LNCipedia: a database for annotated human lncRNA transcript sequences and structures., Nucleic Acids Res.
  165. Wan (2013), Long non-coding RNA ANRIL (CDKN2B-AS) is induced by the ATM-E2F1 signaling pathway., Cell. Signal.
  166. Weinberg (2013), Long non-coding RNA targeting and transcriptional de-repression., Nucleic Acid Ther
  167. Wood (2013), Sense-antisense gene pairs: sequence, transcription, and structure are not conserved between human and mouse., Front Genet
  168. Wu (2013), Hypomethylation of noncoding DNA regions and overexpression of the long noncoding RNA, AFAP1-AS1, in Barrett's esophagus and esophageal adenocarcinoma., Gastroenterology
  169. Wu (2013), Binding interactions between long noncoding RNA HOTAIR and PRC2 proteins., Biochemistry
  170. Yi (2013), RNA-seq identified a super-long intergenic transcript functioning in adipogenesis., RNA Biol
  171. Zhang (2013), Circular intronic long noncoding RNAs., Mol. Cell
  172. Ørom (2013), Long noncoding RNAs usher in a new era in the biology of enhancers., Cell
  173. Amos-Landgraf (2012), The many ways to open the gate to colon cancer., Cell Cycle
  174. Anguera (2012), Molecular signatures of human induced pluripotent stem cells highlight sex differences and cancer genes., Cell Stem Cell
  175. Augoff (2012), miR-31 and its host gene lncRNA LOC554202 are regulated by promoter hypermethylation in triple-negative breast cancer., Mol. Cancer
  176. Bovolenta (2012), The DMD locus harbours multiple long non-coding RNAs which orchestrate and control transcription of muscle dystrophin mRNA isoforms., PLoS ONE
  177. Bánfai (2012), Long noncoding RNAs are rarely translated in two human cell lines., Genome Res.
  178. Cabianca (2012), A long ncRNA links copy number variation to a polycomb/trithorax epigenetic switch in FSHD muscular dystrophy., Cell
  179. Cabianca (2012), A novel molecular mechanism in human genetic disease: a DNA repeat-derived lncRNA., RNA Biol
  180. Derrien (2012), The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression., Genome Res.
  181. Flockhart (2012), BRAFV600E remodels the melanocyte transcriptome and induces BANCR to regulate melanoma cell migration., Genome Res.
  182. Glazko (2012), Computational prediction of polycomb-associated long non-coding RNAs., PLoS ONE
  183. Grant (2012), Rsx is a metatherian RNA with Xist-like properties in X-chromosome inactivation., Nature
  184. Jalali (2012), Integrative transcriptome analysis suggest processing of a subset of long non-coding RNAs to small RNAs., Biol. Direct
  185. Li (2012), AS1DHRS4, a head-to-head natural antisense transcript, silences the DHRS4 gene cluster in cis and trans., Proc. Natl. Acad. Sci. U.S.A.
  186. Maenner (2012), Roles of long, non-coding RNA in chromosome-wide transcription regulation: lessons from two dosage compensation systems., Biochimie
  187. Markaki (2012), The potential of 3D-FISH and super-resolution structured illumination microscopy for studies of 3D nuclear architecture: 3D structured illumination microscopy of defined chromosomal structures visualized by 3D (immuno)-FISH opens new perspectives for studies of nuclear architecture., Bioessays
  188. Maruyama (2012), Altered antisense-to-sense transcript ratios in breast cancer., Proc. Natl. Acad. Sci. U.S.A.
  189. Miyagawa (2012), Identification of cis- and trans-acting factors involved in the localization of MALAT-1 noncoding RNA to nuclear speckles., RNA
  190. Naganuma (2012), Alternative 3'-end processing of long noncoding RNA initiates construction of nuclear paraspeckles., EMBO J.
  191. Niazi (2012), Computational analysis of functional long noncoding RNAs reveals lack of peptide-coding capacity and parallels with 3' UTRs., RNA
  192. Novikova (2012), Structural architecture of the human long non-coding RNA, steroid receptor RNA activator., Nucleic Acids Res.
  193. Pei (2012), The GENCODE pseudogene resource., Genome Biol.
  194. Pinter (2012), Spreading of X chromosome inactivation via a hierarchy of defined Polycomb stations., Genome Res.
  195. Pollex (2012), Recent advances in X-chromosome inactivation research., Curr. Opin. Cell Biol.
  196. Sati (2012), Genome-wide analysis reveals distinct patterns of epigenetic features in long non-coding RNA loci., Nucleic Acids Res.
  197. Tilgner (2012), Deep sequencing of subcellular RNA fractions shows splicing to be predominantly co-transcriptional in the human genome but inefficient for lncRNAs., Genome Res.
  198. Troy (2012), Genetic "lnc"-age of noncoding RNAs to human disease., J. Clin. Invest.
  199. Vizoso (2012), The activatory long non-coding RNA DBE-T reveals the epigenetic etiology of facioscapulohumeral muscular dystrophy., Cell Res.
  200. Wilusz (2012), HuR and translation--the missing linc(RNA)., Mol. Cell
  201. Arthold (2011), Mechanistic insights into chromosome-wide silencing in X inactivation., Hum. Genet.
  202. Bruck (2011), Meta-analysis of the heterogeneity of X chromosome inactivation in human pluripotent stem cells., Stem Cell Res
  203. Chaumeil (2011), Evolution from XIST-independent to XIST-controlled X-chromosome inactivation: epigenetic modifications in distantly related mammals., PLoS ONE
  204. Chureau (2011), Ftx is a non-coding RNA which affects Xist expression and chromatin structure within the X-inactivation center region., Hum. Mol. Genet.
  205. Derrien (2011), [Long non-coding RNAs with enhancer-like function in human cells]., Med Sci (Paris)
  206. Duszczyk (2011), The Xist RNA A-repeat comprises a novel AUCG tetraloop fold and a platform for multimerization., RNA
  207. Hasegawa (2011), Revisiting the function of nuclear scaffold/matrix binding proteins in X chromosome inactivation., RNA Biol
  208. Horvath (2011), Comparative analysis of the primate X-inactivation center region and reconstruction of the ancestral primate XIST locus., Genome Res.
  209. Jeon (2011), YY1 tethers Xist RNA to the inactive X nucleation center., Cell
  210. Knowling (2011), Non-coding RNA and antisense RNA. Nature's trash or treasure?, Biochimie
  211. Morris (2011), Modulation of gene-specific epigenetic states and transcription by non-coding RNAs., Clin Epigenetics
  212. Nakagawa (2011), eXIST with matrix-associated proteins., Trends Cell Biol.
  213. Navarro (2011), [Epigenetic reprogramming: the importance of X inactivation]., Med Sci (Paris)
  214. Okamoto (2011), Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development., Nature
  215. Paralkar (2011), A new 'Linc' between noncoding RNAs and blood development., Genes Dev.
  216. Salmena (2011), A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language?, Cell
  217. Saxena (2011), Long non-coding RNA modifies chromatin: epigenetic silencing by long non-coding RNAs., Bioessays
  218. Splinter (2011), The inactive X chromosome adopts a unique three-dimensional conformation that is dependent on Xist RNA., Genes Dev.
  219. Weakley (2011), Expression and function of a large non-coding RNA gene XIST in human cancer., World J Surg
  220. Zhao (2011), Molecular and DNA methylation analysis of Peg10 and Xist gene in sheep., Mol. Biol. Rep.
  221. Hall (2010), XIST RNA and architecture of the inactive X chromosome: implications for the repeat genome., Cold Spring Harb. Symp. Quant. Biol.
  222. Hasegawa (2010), The matrix protein hnRNP U is required for chromosomal localization of Xist RNA., Dev. Cell
  223. Kaneko (2010), Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA., Genes Dev.
  224. Kanhere (2010), Short RNAs are transcribed from repressed polycomb target genes and interact with polycomb repressive complex-2., Mol. Cell
  225. Lengner (2010), Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations., Cell
  226. Maenner (2010), 2-D structure of the A region of Xist RNA and its implication for PRC2 association., PLoS Biol.
  227. Marchetto (2010), A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells., Cell
  228. Moreira de Mello (2010), Random X inactivation and extensive mosaicism in human placenta revealed by analysis of allele-specific gene expression along the X chromosome., PLoS ONE
  229. Sarma (2010), Locked nucleic acids (LNAs) reveal sequence requirements and kinetics of Xist RNA localization to the X chromosome., Proc. Natl. Acad. Sci. U.S.A.
  230. Tchieu (2010), Female human iPSCs retain an inactive X chromosome., Cell Stem Cell
  231. Zhao (2010), Genome-wide identification of polycomb-associated RNAs by RIP-seq., Mol. Cell
  232. Deakin (2009), Unravelling the evolutionary origins of X chromosome inactivation in mammals: insights from marsupials and monotremes., Chromosome Res.
  233. Hanna (2009), Direct cell reprogramming is a stochastic process amenable to acceleration., Nature
  234. Kanellopoulou (2009), X chromosome inactivation in the absence of Dicer., Proc. Natl. Acad. Sci. U.S.A.
  235. Elisaphenko (2008), A dual origin of the Xist gene from a protein-coding gene and a set of transposable elements., PLoS ONE
  236. Hall (2008), X-inactivation reveals epigenetic anomalies in most hESC but identifies sublines that initiate as expected., J. Cell. Physiol.
  237. Ogawa (2008), Intersection of the RNA interference and X-inactivation pathways., Science
  238. Shen (2008), X-inactivation in female human embryonic stem cells is in a nonrandom pattern and prone to epigenetic alterations., Proc. Natl. Acad. Sci. U.S.A.
  239. Silva (2008), X-chromosome inactivation and epigenetic fluidity in human embryonic stem cells., Proc. Natl. Acad. Sci. U.S.A.
  240. Zhao (2008), Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome., Science
  241. Davidow (2007), The search for a marsupial XIC reveals a break with vertebrate synteny., Chromosome Res.
  242. Hore (2007), The region homologous to the X-chromosome inactivation centre has been disrupted in marsupial and monotreme mammals., Chromosome Res.
  243. Shevchenko (2007), Genes flanking Xist in mouse and human are separated on the X chromosome in American marsupials., Chromosome Res.
  244. Zhang (2007), Perinucleolar targeting of the inactive X during S phase: evidence for a role in the maintenance of silencing., Cell
  245. Chaumeil (2006), A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silenced., Genes Dev.
  246. Duret (2006), The Xist RNA gene evolved in eutherians by pseudogenization of a protein-coding gene., Science
  247. Blackshaw (2004), Genomic analysis of mouse retinal development., PLoS Biol.
  248. Wutz (2002), Chromosomal silencing and localization are mediated by different domains of Xist RNA., Nat. Genet.
  249. Beletskii (2001), PNA interference mapping demonstrates functional domains in the noncoding RNA Xist., Proc. Natl. Acad. Sci. U.S.A.
  250. Csankovszki (2001), Synergism of Xist RNA, DNA methylation, and histone hypoacetylation in maintaining X chromosome inactivation., J. Cell Biol.
  251. Wutz (2000), A shift from reversible to irreversible X inactivation is triggered during ES cell differentiation., Mol. Cell
  252. Csankovszki (1999), Conditional deletion of Xist disrupts histone macroH2A localization but not maintenance of X inactivation., Nat. Genet.
  253. Marahrens (1997), Xist-deficient mice are defective in dosage compensation but not spermatogenesis., Genes Dev.
  254. Sheardown (1997), Stabilization of Xist RNA mediates initiation of X chromosome inactivation., Cell
  255. Clemson (1996), XIST RNA paints the inactive X chromosome at interphase: evidence for a novel RNA involved in nuclear/chromosome structure., J. Cell Biol.
  256. Penny (1996), Requirement for Xist in X chromosome inactivation., Nature
  257. Brockdorff (1992), The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus., Cell
  258. Brown (1992), The human XIST gene: analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus., Cell
  259. Borsani (1991), Characterization of a murine gene expressed from the inactive X chromosome., Nature
  260. Brockdorff (1991), Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome., Nature
  261. Brown (1991), A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome., Nature

LNCipedia transcript ID history

LNCipedia version LNCipedia transcript ID
4.1 XIST:48
5.0 XIST:48
5.1 XIST:48
5.2 XIST:48