Transcript: lnc-BMP6-106:11

Basic information

LNCipedia transcript ID: lnc-BMP6-106:11 
LNCipedia gene ID: lnc-BMP6-106
Ensembl Gene ID: ENSG00000232234
Ensembl Transcript ID: ENST00000644216
Location (hg38): chr6:8165512-8182862
Strand: +
Class: intergenic
Sequence Ontology term: lincRNA
Transcript size: 997 bp
Exons: 3
Sources: Ensembl release 92 - Apr 2018
Alternative transcript names: ENST00000644216.1
Alternative gene names: ENSG00000232234.3; AL355499.1


RNA sequence:

Structure:

Protein coding potential

Metric Raw result Interpretation
PRIDE reprocessing 2.0 0 non-coding 
Lee translation initiation sites non-coding 
PhyloCSF score -60.344 non-coding 
CPAT coding probability 5.99% non-coding 
Bazzini small ORFs 0 non-coding 

In stringent set: yes

Locus conservation

Locus conservation?
lnc-BMP6-106:11 no no no no

Available literature

  1. Lu (2016), Long non-coding RNA HULC promotes tumor angiogenesis in liver cancer by up-regulating sphingosine kinase 1 (SPHK1)., Oncotarget
  2. Wan (2016), miR-203 suppresses the proliferation and metastasis of hepatocellular carcinoma by targeting oncogene ADAM9 and oncogenic long non-coding RNA HULC., Anticancer Agents Med Chem
  3. Xie (2016), Long non-coding RNAs in colorectal cancer., Oncotarget
  4. Ching (2015), Non-coding yet non-trivial: a review on the computational genomics of lincRNAs., BioData Min
  5. Conigliaro (2015), CD90+ liver cancer cells modulate endothelial cell phenotype through the release of exosomes containing H19 lncRNA., Mol. Cancer
  6. Cui (2015), Long noncoding RNA HULC modulates abnormal lipid metabolism in hepatoma cells through an miR-9-mediated RXRA signaling pathway., Cancer Res.
  7. Cui (2015), A long noncoding RNA perturbs the circadian rhythm of hepatoma cells to facilitate hepatocarcinogenesis., Neoplasia
  8. Gandhy (2015), Specificity protein (Sp) transcription factors and metformin regulate expression of the long non-coding RNA HULC., Oncotarget
  9. Ge (2015), MiRNA-192 [corrected] and miRNA-204 Directly Suppress lncRNA HOTTIP and Interrupt GLS1-Mediated Glutaminolysis in Hepatocellular Carcinoma., PLoS Genet.
  10. Guerrieri (2015), Long non-coding RNAs era in liver cancer., World J Hepatol
  11. Gui (2015), Long Noncoding RNA CUDR Regulates HULC and β-Catenin to Govern Human Liver Stem Cell Malignant Differentiation., Mol. Ther.
  12. Guo (2015), Comprehensive analysis of lncRNA-mRNA co-expression patterns identifies immune-associated lncRNA biomarkers in ovarian cancer malignant progression., Sci Rep
  13. Huang (2015), Long non-coding RNA ANRIL is upregulated in hepatocellular carcinoma and regulates cell apoptosis by epigenetic silencing of KLF2., J Hematol Oncol
  14. Huang (2015), Long non-coding RNA TUG1 is up-regulated in hepatocellular carcinoma and promotes cell growth and apoptosis by epigenetically silencing of KLF2., Mol. Cancer
  15. Huang (2015), HBx-related long non-coding RNA DBH-AS1 promotes cell proliferation and survival by activating MAPK signaling in hepatocellular carcinoma., Oncotarget
  16. Jiang (2015), LncRNA2Function: a comprehensive resource for functional investigation of human lncRNAs based on RNA-seq data., BMC Genomics
  17. Kang (2015), Long noncoding RNAs POLR2E rs3787016 C/T and HULC rs7763881 A/C polymorphisms are associated with decreased risk of esophageal cancer., Tumour Biol.
  18. Li (2015), MDR1 will play a key role in pharmacokinetic changes under hypoxia at high altitude and its potential regulatory networks., Drug Metab. Rev.
  19. Li (2015), HULC and Linc00152 Act as Novel Biomarkers in Predicting Diagnosis of Hepatocellular Carcinoma., Cell. Physiol. Biochem.
  20. Liu (2015), Carboplatin-docetaxel-induced activity against ovarian cancer is dependent on up-regulated lncRNA PVT1., Int J Clin Exp Pathol
  21. Liu (2015), Ultrasensitive strategy based on PtPd nanodendrite/nano-flower-like@GO signal amplification for the detection of long non-coding RNA., Biosens Bioelectron
  22. Peng (2015), Long non-coding RNA MEG3 functions as a competing endogenous RNA to regulate gastric cancer progression., J. Exp. Clin. Cancer Res.
  23. Ragusa (2015), Non-coding landscapes of colorectal cancer., World J. Gastroenterol.
  24. Ren (2015), Association of long non-coding RNA HOTTIP with progression and prognosis in colorectal cancer., Int J Clin Exp Pathol
  25. Shen (2015), Exploration of Deregulated Long Non-Coding RNAs in Association with Hepatocarcinogenesis and Survival., Cancers (Basel)
  26. Shi (2015), Microvascular invasion in hepatocellular carcinoma overexpression promotes cell proliferation and inhibits cell apoptosis of hepatocellular carcinoma via inhibiting miR-199a expression., Onco Targets Ther
  27. Sun (2015), Increased expression of lncRNA HULC indicates a poor prognosis and promotes cell metastasis in osteosarcoma., Int J Clin Exp Pathol
  28. Wang (2015), Serum LncRNAs Profiles Serve as Novel Potential Biomarkers for the Diagnosis of HBV-Positive Hepatocellular Carcinoma., PLoS ONE
  29. Yang (2015), LincRNA-p21 activates endoplasmic reticulum stress and inhibits hepatocellular carcinoma., Oncotarget
  30. Yu (2015), Long non-coding RNAs and hepatocellular carcinoma., Mol Clin Oncol
  31. Zhang (2015), Long Noncoding RNA Expression Signatures of Metastatic Nasopharyngeal Carcinoma and Their Prognostic Value., Biomed Res Int
  32. Zhang (2015), Molecular mechanism of HEIH and HULC in the proliferation and invasion of hepatoma cells., Int J Clin Exp Med
  33. Zhao (2015), LncRNA HULC affects the differentiation of Treg in HBV-related liver cirrhosis., Int. Immunopharmacol.
  34. Zhou (2015), Identification of the long non-coding RNA H19 in plasma as a novel biomarker for diagnosis of gastric cancer., Sci Rep
  35. Chiyomaru (2014), Long non-coding RNA HOTAIR is targeted and regulated by miR-141 in human cancer cells., J. Biol. Chem.
  36. Das (2014), lnCeDB: database of human long noncoding RNA acting as competing endogenous RNA., PLoS ONE
  37. Ghosal (2014), HumanViCe: host ceRNA network in virus infected cells in human., Front Genet
  38. Guo (2014), BRAF-activated long non-coding RNA contributes to colorectal cancer migration by inducing epithelial-mesenchymal transition., Oncol Lett
  39. Han (2014), LEIGC long non-coding RNA acts as a tumor suppressor in gastric carcinoma by inhibiting the epithelial-to-mesenchymal transition., BMC Cancer
  40. He (2014), Reciprocal regulation of PCGEM1 and miR-145 promote proliferation of LNCaP prostate cancer cells., J. Exp. Clin. Cancer Res.
  41. Huang (2014), Characteristics of long non-coding RNA and its relation to hepatocellular carcinoma., Carcinogenesis
  42. Lau (2014), Viral-human chimeric transcript predisposes risk to liver cancer development and progression., Cancer Cell
  43. Li (2014), Comparison of long non‑coding RNAs, microRNAs and messenger RNAs involved in initiation and progression of esophageal squamous cell carcinoma., Mol Med Rep
  44. Ma (2014), Long non-coding RNA HOTAIR, a c-Myc activated driver of malignancy, negatively regulates miRNA-130a in gallbladder cancer., Mol. Cancer
  45. Malek (2014), Correlation of long non-coding RNA expression with metastasis, drug resistance and clinical outcome in cancer., Oncotarget
  46. Peng (2014), Long noncoding RNA HULC is a novel biomarker of poor prognosis in patients with pancreatic cancer., Med. Oncol.
  47. Su (2014), Comprehensive analysis of long non-coding RNAs in human breast cancer clinical subtypes., Oncotarget
  48. Tong (2014), Association of decreased expression of long non-coding RNA LOC285194 with chemoradiotherapy resistance and poor prognosis in esophageal squamous cell carcinoma., J Transl Med
  49. Xu (2014), Long non-coding RNA URHC regulates cell proliferation and apoptosis via ZAK through the ERK/MAPK signaling pathway in hepatocellular carcinoma., Int. J. Biol. Sci.
  50. Zhao (2014), Role of long non-coding RNA HULC in cell proliferation, apoptosis and tumor metastasis of gastric cancer: a clinical and in vitro investigation., Oncol. Rep.
  51. Zhao (2014), Role of HOTAIR long noncoding RNA in metastatic progression of lung cancer., Eur Rev Med Pharmacol Sci
  52. Du (2013), Integrative genomic analyses reveal clinically relevant long noncoding RNAs in human cancer., Nat. Struct. Mol. Biol.
  53. Hämmerle (2013), Posttranscriptional destabilization of the liver-specific long noncoding RNA HULC by the IGF2 mRNA-binding protein 1 (IGF2BP1)., Hepatology
  54. Jalali (2013), Systematic transcriptome wide analysis of lncRNA-miRNA interactions., PLoS ONE
  55. Kapusta (2013), Transposable elements are major contributors to the origin, diversification, and regulation of vertebrate long noncoding RNAs., PLoS Genet.
  56. Kogure (2013), Extracellular Vesicle-Mediated Transfer of a Novel Long Noncoding RNA TUC339: A Mechanism of Intercellular Signaling in Human Hepatocellular Cancer., Genes Cancer
  57. Qiao (2013), LncRNA DQ786243 affects Treg related CREB and Foxp3 expression in Crohn's disease., J. Biomed. Sci.
  58. Su (2013), microRNAs and ceRNAs: RNA networks in pathogenesis of cancer., Chin. J. Cancer Res.
  59. Tang (2013), Long noncoding RNAs-related diseases, cancers, and drugs., ScientificWorldJournal
  60. Tang (2013), Long noncoding RNA HOTAIR is associated with motility, invasion, and metastatic potential of metastatic melanoma., Biomed Res Int
  61. Volders (2013), LNCipedia: a database for annotated human lncRNA transcript sequences and structures., Nucleic Acids Res.
  62. Wan (2013), Long non-coding RNA ANRIL (CDKN2B-AS) is induced by the ATM-E2F1 signaling pathway., Cell. Signal.
  63. Weber (2013), Evaluation of long noncoding RNA MALAT1 as a candidate blood-based biomarker for the diagnosis of non-small cell lung cancer., BMC Res Notes
  64. Wu (2013), Hypomethylation of noncoding DNA regions and overexpression of the long noncoding RNA, AFAP1-AS1, in Barrett's esophagus and esophageal adenocarcinoma., Gastroenterology
  65. Wu (2013), A genetic polymorphism in lincRNA-uc003opf.1 is associated with susceptibility to esophageal squamous cell carcinoma in Chinese populations., Carcinogenesis
  66. Wu (2013), Ets-2 regulates cell apoptosis via the Akt pathway, through the regulation of urothelial cancer associated 1, a long non-coding RNA, in bladder cancer cells., PLoS ONE
  67. Xie (2013), Plasma HULC as a promising novel biomarker for the detection of hepatocellular carcinoma., Biomed Res Int
  68. Du (2012), Elevation of highly up-regulated in liver cancer (HULC) by hepatitis B virus X protein promotes hepatoma cell proliferation via down-regulating p18., J. Biol. Chem.
  69. Jeggari (2012), miRcode: a map of putative microRNA target sites in the long non-coding transcriptome., Bioinformatics
  70. Liu (2012), A genetic variant in long non-coding RNA HULC contributes to risk of HBV-related hepatocellular carcinoma in a Chinese population., PLoS ONE
  71. Scaria (2012), Long Non-Coding RNAs in Infection Biology., Front Genet
  72. Braconi (2011), microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer., Oncogene
  73. Chan (2011), Genome-wide association study of hepatocellular carcinoma in Southern Chinese patients with chronic hepatitis B virus infection., PLoS ONE
  74. Salmena (2011), A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language?, Cell
  75. Tahira (2011), Long noncoding intronic RNAs are differentially expressed in primary and metastatic pancreatic cancer., Mol. Cancer


LNCipedia transcript ID history

LNCipedia version LNCipedia transcript ID
5.0 lnc-PRPF4B-106:11
5.1 lnc-PRPF4B-106:11
5.2 lnc-BMP6-106:11