Transcript: lnc-FBXO9-1:1

Basic information

LNCipedia transcript ID: lnc-FBXO9-1:1 
LNCipedia gene ID: lnc-FBXO9-1
Location (hg38): chr6:52995619-52995951
Strand: +
Class: intergenic
Sequence Ontology term: lincRNA
Transcript size: 333 bp
Exons: 1
Sources: long non-coding rna db - lncrnadb.com
Alternative transcript names: 7SK; 7-3 RNA; K-RNA; 7SK-RNA; 7SK snRNA; RN7SK
Alternative gene names:


RNA sequence:

Structure:

Protein coding potential

Metric Raw result Interpretation
PRIDE reprocessing 2.0 0 non-coding 
Lee translation initiation sites 1 non-coding 
PhyloCSF score 46.8024 non-coding 
CPAT coding probability 7.53% non-coding 
Bazzini small ORFs 0 non-coding 

In stringent set: no

Locus conservation

Locus conservation?
lnc-FBXO9-1:1 no no no no

Available literature

  1. Lennox (2016), Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides., Nucleic Acids Res.
  2. Hu (2015), A common set of distinct features that characterize noncoding RNAs across multiple species., Nucleic Acids Res.
  3. Keramati (2015), 7SK small nuclear RNA inhibits cancer cell proliferation through apoptosis induction., Tumour Biol.
  4. Kraus (2015), Long non-coding RNA normalisers in human brain tissue., J Neural Transm (Vienna)
  5. Na (2015), Long non-coding RNA UCA1 contributes to the progression of prostate cancer and regulates proliferation through KLF4-KRT6/13 signaling pathway., Int J Clin Exp Med
  6. Pei (2015), Notch-1 promotes breast cancer cells proliferation by regulating LncRNA GAS5., Int J Clin Exp Med
  7. Rice (2015), Roles of microRNAs and long-noncoding RNAs in human immunodeficiency virus replication., Wiley Interdiscip Rev RNA
  8. Tantai (2015), Combined identification of long non-coding RNA XIST and HIF1A-AS1 in serum as an effective screening for non-small cell lung cancer., Int J Clin Exp Pathol
  9. Wang (2015), Upregulated lncRNA-UCA1 contributes to progression of lung cancer and is closely related to clinical diagnosis as a predictive biomarker in plasma., Int J Clin Exp Med
  10. Xiong (2015), STAT3‑regulated long non‑coding RNAs lnc‑7SK and lnc‑IGF2‑AS promote hepatitis C virus replication., Mol Med Rep
  11. Abdelmohsen (2013), Senescence-associated lncRNAs: senescence-associated long noncoding RNAs., Aging Cell
  12. Castle (2010), Digital genome-wide ncRNA expression, including SnoRNAs, across 11 human tissues using polyA-neutral amplification., PLoS ONE
  13. D'Orso (2010), RNA-mediated displacement of an inhibitory snRNP complex activates transcription elongation., Nat. Struct. Mol. Biol.
  14. Mondal (2010), Characterization of the RNA content of chromatin., Genome Res.
  15. Raha (2010), Close association of RNA polymerase II and many transcription factors with Pol III genes., Proc. Natl. Acad. Sci. U.S.A.
  16. Sobhian (2010), HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP., Mol. Cell
  17. Xue (2010), A capping-independent function of MePCE in stabilizing 7SK snRNA and facilitating the assembly of 7SK snRNP., Nucleic Acids Res.
  18. Barboric (2009), 7SK snRNP/P-TEFb couples transcription elongation with alternative splicing and is essential for vertebrate development., Proc. Natl. Acad. Sci. U.S.A.
  19. Marz (2009), Evolution of 7SK RNA and its protein partners in metazoa., Mol. Biol. Evol.
  20. Gruber (2008), Invertebrate 7SK snRNAs., J. Mol. Evol.
  21. Gruber (2008), Arthropod 7SK RNA., Mol. Biol. Evol.
  22. Barrandon (2007), The transcription-dependent dissociation of P-TEFb-HEXIM1-7SK RNA relies upon formation of hnRNP-7SK RNA complexes., Mol. Cell. Biol.
  23. Jeronimo (2007), Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme., Mol. Cell
  24. Young (2007), Cellular mRNA activates transcription elongation by displacing 7SK RNA., PLoS ONE
  25. He (2006), Regulation of two key nuclear enzymatic activities by the 7SK small nuclear RNA., Cold Spring Harb. Symp. Quant. Biol.
  26. Chen (2004), Phosphorylated positive transcription elongation factor b (P-TEFb) is tagged for inhibition through association with 7SK snRNA., J. Biol. Chem.
  27. Blencowe (2002), Transcription: surprising role for an elusive small nuclear RNA., Curr. Biol.
  28. Nguyen (2001), 7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes., Nature
  29. Yang (2001), The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription., Nature
  30. Gürsoy (2000), The vertebrate 7S K RNA separates hagfish (Myxine glutinosa) and lamprey (Lampetra fluviatilis)., J. Mol. Evol.
  31. Krause (1996), Chromatin structure and function: the heretical path to an RNA transcription factor., Biochem. Cell Biol.
  32. Wassarman (1991), Structural analyses of the 7SK ribonucleoprotein (RNP), the most abundant human small RNP of unknown function., Mol. Cell. Biol.
  33. Krüger (1987), Structural and functional analysis of a human 7 S K RNA gene., J. Mol. Biol.
  34. Reddy (1984), Primary and secondary structure of 7-3 (K) RNA of Novikoff hepatoma., J. Biol. Chem.
  35. Sohn (1983), 7S-K nuclear RNA from simian virus 40-transformed cells has sequence homology to the viral early promoter., Proc. Natl. Acad. Sci. U.S.A.
  36. Zieve (1976), Small RNA species of the HeLa cell: metabolism and subcellular localization., Cell


LNCipedia transcript ID history

LNCipedia version LNCipedia transcript ID
1.3 lnc-FBXO9-1:1
3.1 lnc-FBXO9-1:1
4.0 lnc-FBXO9-1:1
4.1 lnc-FBXO9-1:1
5.0 lnc-FBXO9-1:1
5.1 lnc-EFHC1-9:2
5.2 lnc-FBXO9-1:1