Gene: PVT1

Basic information

LNCipedia gene ID: PVT1 
Location (hg38): chr8:127794523-128188211
Strand: +
Class: intergenic
Sequence Ontology term: lincRNA_gene
Transcripts: 83

Transcripts

Transcript IDLocation (hg38)Length
PVT1:1 chr8:127794523-128101088 1200 bp
PVT1:10 chr8:127794557-127855319 343 bp
PVT1:11 chr8:127794557-127855319 458 bp
PVT1:12 chr8:127794557-127940454 1535 bp
PVT1:13 chr8:127794560-127939609 392 bp
PVT1:14 chr8:127794575-127890952 938 bp
PVT1:15 chr8:127795754-127890932 599 bp
PVT1:16 chr8:127795813-127890795 568 bp
PVT1:17 chr8:127795820-127890960 624 bp
PVT1:18 chr8:127796033-127890983 844 bp
PVT1:19 chr8:127854728-127890741 221 bp
PVT1:2 chr8:127794523-127932697 855 bp
PVT1:20 chr8:127855148-127932688 806 bp
PVT1:21 chr8:127855148-127932688 1218 bp
PVT1:22 chr8:127863715-128009638 1561 bp
PVT1:23 chr8:127890628-128101253 1699 bp
PVT1:24 chr8:127890646-127932695 584 bp
PVT1:25 chr8:127890677-127996650 542 bp
PVT1:26 chr8:127890870-127996650 518 bp
PVT1:27 chr8:127976248-127994931 230 bp
PVT1:28 chr8:127982450-127994931 209 bp
PVT1:29 chr8:127984020-127997041 796 bp
PVT1:3 chr8:127794523-128101088 1536 bp
PVT1:30 chr8:127984173-127994931 211 bp
PVT1:31 chr8:127988677-127992074 1836 bp
PVT1:32 chr8:127989184-128070272 383 bp
PVT1:33 chr8:127989217-128096578 408 bp
PVT1:34 chr8:127989261-128096656 922 bp
PVT1:35 chr8:128009658-128101097 443 bp
PVT1:36 chr8:128070157-128101227 498 bp
PVT1:37 chr8:128070163-128101245 602 bp
PVT1:38 chr8:128070322-128099898 706 bp
PVT1:39 chr8:128082687-128101257 577 bp
PVT1:4 chr8:127794533-127890975 754 bp
PVT1:40 chr8:128084521-128101242 501 bp
PVT1:41 chr8:128084521-128101242 705 bp
PVT1:42 chr8:128091094-128101242 660 bp
PVT1:43 chr8:128091094-128101242 864 bp
PVT1:44 chr8:128095813-128101227 390 bp
PVT1:45 chr8:128096519-128099887 654 bp
PVT1:46 chr8:128099072-128101242 620 bp
PVT1:47 chr8:128099352-128101183 426 bp
PVT1:48 chr8:128099509-128101240 326 bp
PVT1:49 chr8:127794541-127855319 359 bp
PVT1:5 chr8:127794533-128101252 1900 bp
PVT1:50 chr8:127794541-127855319 474 bp
PVT1:51 chr8:127794541-127890952 972 bp
PVT1:52 chr8:127794541-127890975 746 bp
PVT1:53 chr8:127794541-127902532 681 bp
PVT1:54 chr8:127794541-127940454 1551 bp
PVT1:55 chr8:127794541-127939609 411 bp
PVT1:56 chr8:127795822-127796028 207 bp
PVT1:57 chr8:127795822-127890960 622 bp
PVT1:58 chr8:127795822-128101256 1933 bp
PVT1:59 chr8:127795822-127890795 559 bp
PVT1:6 chr8:127794554-128101256 5132 bp
PVT1:60 chr8:127795822-127890983 1055 bp
PVT1:61 chr8:127795822-127953968 710 bp
PVT1:62 chr8:127795822-128073429 1125 bp
PVT1:63 chr8:127795822-127890932 531 bp
PVT1:64 chr8:127890621-127902548 471 bp
PVT1:65 chr8:127890621-127932126 452 bp
PVT1:66 chr8:127890621-127932695 609 bp
PVT1:67 chr8:127890621-128101253 1706 bp
PVT1:68 chr8:127890621-127996650 598 bp
PVT1:69 chr8:127932051-127939507 7191 bp
PVT1:7 chr8:127794556-127999226 2164 bp
PVT1:70 chr8:127975956-127982131 2371 bp
PVT1:71 chr8:127975956-128101262 1262 bp
PVT1:72 chr8:127975956-127994984 575 bp
PVT1:73 chr8:127975956-127999437 999 bp
PVT1:74 chr8:127975956-128101262 893 bp
PVT1:75 chr8:127983898-128010444 13144 bp
PVT1:76 chr8:127983898-128073429 666 bp
PVT1:77 chr8:127983898-128101262 1113 bp
PVT1:78 chr8:127983898-128101262 970 bp
PVT1:79 chr8:127983898-128188211 19273 bp
PVT1:8 chr8:127794556-128101088 1221 bp
PVT1:80 chr8:127997076-127998192 1117 bp
PVT1:81 chr8:128049409-128073429 569 bp
PVT1:82 chr8:128049409-128113581 13079 bp
PVT1:83 chr8:127794533-128101253 1940 bp
PVT1:9 chr8:127794556-128101088 1334 bp

Locus conservation

Locus conservation?
PVT1 no no no no

Available literature

  1. Austin (2017), Transcriptional profiling identifies the long noncoding RNA plasmacytoma variant translocation (PVT1) as a novel regulator of the asthmatic phenotype in human airway smooth muscle., J. Allergy Clin. Immunol.
  2. Cui (2016), Long non-coding RNA PVT1 as a novel biomarker for diagnosis and prognosis of non-small cell lung cancer., Tumour Biol.
  3. Li (2016), Cancer RNA-Seq Nexus: a database of phenotype-specific transcriptome profiling in cancer cells., Nucleic Acids Res.
  4. Zhou (2016), Long noncoding RNA PVT1 modulates thyroid cancer cell proliferation by recruiting EZH2 and regulating thyroid-stimulating hormone receptor (TSHR)., Tumour Biol.
  5. Cabanski (2015), Pan-cancer transcriptome analysis reveals long noncoding RNAs with conserved function., RNA Biol
  6. Colombo (2015), PVT1: a rising star among oncogenic long noncoding RNAs., Biomed Res Int
  7. Ding (2015), Long non-coding RNA PVT1 is associated with tumor progression and predicts recurrence in hepatocellular carcinoma patients., Oncol Lett
  8. Guo (2015), Competing endogenous RNA networks and gastric cancer., World J. Gastroenterol.
  9. Huang (2015), Increased expression of the lncRNA PVT1 is associated with poor prognosis in pancreatic cancer patients., Minerva Med.
  10. Kim (2015), MYC-repressed long noncoding RNAs antagonize MYC-induced cell proliferation and cell cycle progression., Oncotarget
  11. Kong (2015), Long noncoding RNA PVT1 indicates a poor prognosis of gastric cancer and promotes cell proliferation through epigenetically regulating p15 and p16., Mol. Cancer
  12. Liu (2015), Carboplatin-docetaxel-induced activity against ovarian cancer is dependent on up-regulated lncRNA PVT1., Int J Clin Exp Pathol
  13. Malouf (2015), Characterization of long non-coding RNA transcriptome in clear-cell renal cell carcinoma by next-generation deep sequencing., Mol Oncol
  14. Na (2015), Long non-coding RNA UCA1 contributes to the progression of prostate cancer and regulates proliferation through KLF4-KRT6/13 signaling pathway., Int J Clin Exp Med
  15. Pei (2015), Notch-1 promotes breast cancer cells proliferation by regulating LncRNA GAS5., Int J Clin Exp Med
  16. Ragusa (2015), Non-coding landscapes of colorectal cancer., World J. Gastroenterol.
  17. Shih (2015), Non-Coding RNAs in Castration-Resistant Prostate Cancer: Regulation of Androgen Receptor Signaling and Cancer Metabolism., Int J Mol Sci
  18. Tantai (2015), Combined identification of long non-coding RNA XIST and HIF1A-AS1 in serum as an effective screening for non-small cell lung cancer., Int J Clin Exp Pathol
  19. Wei (2015), Transcriptome profiling of esophageal squamous cell carcinoma reveals a long noncoding RNA acting as a tumor suppressor., Oncotarget
  20. Xue (2015), Decreased expression of long non-coding RNA NBAT-1 is associated with poor prognosis in patients with clear cell renal cell carcinoma., Int J Clin Exp Pathol
  21. Younger (2015), Integrative genomic analysis reveals widespread enhancer regulation by p53 in response to DNA damage., Nucleic Acids Res.
  22. Yu (2015), Cardiac hypertrophy is positively regulated by long non-coding RNA PVT1., Int J Clin Exp Pathol
  23. Zeng (2015), Overexpression of the long non-coding RNA PVT1 is correlated with leukemic cell proliferation in acute promyelocytic leukemia., J Hematol Oncol
  24. Zhang (2015), Overexpression of long non-coding RNA PVT1 in gastric cancer cells promotes the development of multidrug resistance., Biochem. Biophys. Res. Commun.
  25. Zhang (2015), Cancer Specific Long Noncoding RNAs Show Differential Expression Patterns and Competing Endogenous RNA Potential in Hepatocellular Carcinoma., PLoS ONE
  26. Zhou (2015), Identification of the long non-coding RNA H19 in plasma as a novel biomarker for diagnosis of gastric cancer., Sci Rep
  27. Zhuang (2015), Tetracycline-inducible shRNA targeting long non-coding RNA PVT1 inhibits cell growth and induces apoptosis in bladder cancer cells., Oncotarget
  28. Alaimo (2014), ncPred: ncRNA-Disease Association Prediction through Tripartite Network-Based Inference., Front Bioeng Biotechnol
  29. Athie (2014), FAL1ing inside an amplicon., Cancer Cell
  30. Chinen (2014), 8q24 amplified segments involve novel fusion genes between NSMCE2 and long noncoding RNAs in acute myelogenous leukemia., J Hematol Oncol
  31. Ding (2014), Expression and clinical significance of the long non-coding RNA PVT1 in human gastric cancer., Onco Targets Ther
  32. Dryden (2014), Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C., Genome Res.
  33. Garzon (2014), Expression and prognostic impact of lncRNAs in acute myeloid leukemia., Proc. Natl. Acad. Sci. U.S.A.
  34. Johnsson (2014), Expanding the functional role of long noncoding RNAs., Cell Res.
  35. Kim (2014), Novel fusion transcripts in human gastric cancer revealed by transcriptome analysis., Oncogene
  36. Li (2014), Discovery of Protein-lncRNA Interactions by Integrating Large-Scale CLIP-Seq and RNA-Seq Datasets., Front Bioeng Biotechnol
  37. Paci (2014), Computational analysis identifies a sponge interaction network between long non-coding RNAs and messenger RNAs in human breast cancer., BMC Syst Biol
  38. Perry (2014), Role of non-coding RNAs in maintaining primary airway smooth muscle cells., Respir. Res.
  39. Su (2014), Comprehensive analysis of long non-coding RNAs in human breast cancer clinical subtypes., Oncotarget
  40. Takahashi (2014), Amplification of PVT-1 is involved in poor prognosis via apoptosis inhibition in colorectal cancers., Br. J. Cancer
  41. Tseng (2014), PVT1 dependence in cancer with MYC copy-number increase., Nature
  42. Wan (2014), Noncoding RNAs in DNA repair and genome integrity., Antioxid. Redox Signal.
  43. Wang (2014), Oncofetal long noncoding RNA PVT1 promotes proliferation and stem cell-like property of hepatocellular carcinoma cells by stabilizing NOP2., Hepatology
  44. Wang (2014), Characteristics of PVT1 and its roles in diseases., Chin. Med. Sci. J.
  45. Yang (2014), A network based method for analysis of lncRNA-disease associations and prediction of lncRNAs implicated in diseases., PLoS ONE
  46. Yang (2014), Increased expression of the lncRNA PVT1 promotes tumorigenesis in non-small cell lung cancer., Int J Clin Exp Pathol
  47. Zhang (2014), Frequent mutation of rs13281615 and its association with PVT1 expression and cell proliferation in breast cancer., J Genet Genomics
  48. Alvarez (2013), Role of microRNA 1207-5P and its host gene, the long non-coding RNA Pvt1, as mediators of extracellular matrix accumulation in the kidney: implications for diabetic nephropathy., PLoS ONE
  49. Bisio (2013), Identification of new p53 target microRNAs by bioinformatics and functional analysis., BMC Cancer
  50. Cao (2013), Analysis of long non-coding RNA expression profiles in gastric cancer., World J. Gastroenterol.
  51. Du (2013), Integrative genomic analyses reveal clinically relevant long noncoding RNAs in human cancer., Nat. Struct. Mol. Biol.
  52. Alvarez (2011), Functional characterization of the plasmacytoma variant translocation 1 gene (PVT1) in diabetic nephropathy., PLoS ONE
  53. You (2011), Genome-wide screen identifies PVT1 as a regulator of Gemcitabine sensitivity in human pancreatic cancer cells., Biochem. Biophys. Res. Commun.
  54. Carramusa (2007), The PVT-1 oncogene is a Myc protein target that is overexpressed in transformed cells., J. Cell. Physiol.