Gene: WT1-AS
Basic information
LNCipedia gene ID: WT1-AS
Location (hg38): chr11:32435518-32458769
Strand: +
Class: antisense
Sequence Ontology term: antisense_lncRNA_gene
Transcripts: 14
Transcripts
| Transcript ID | Location (hg38) | Length |
|---|---|---|
| WT1-AS:10 | chr11:32436039-32440072 | 3027 bp |
| WT1-AS:11 | chr11:32436039-32446715 | 3110 bp |
| WT1-AS:12 | chr11:32436039-32439457 | 2412 bp |
| WT1-AS:13 | chr11:32437623-32438326 | 561 bp |
| WT1-AS:14 | chr11:32437929-32440072 | 2144 bp |
| WT1-AS:15 | chr11:32438370-32439132 | 482 bp |
| WT1-AS:2 | chr11:32435518-32438707 | 1320 bp |
| WT1-AS:3 | chr11:32435518-32438590 | 1075 bp |
| WT1-AS:4 | chr11:32435518-32439457 | 2070 bp |
| WT1-AS:5 | chr11:32435518-32437054 | 589 bp |
| WT1-AS:6 | chr11:32435518-32458769 | 1537 bp |
| WT1-AS:7 | chr11:32435579-32441404 | 3828 bp |
| WT1-AS:8 | chr11:32435776-32437051 | 328 bp |
| WT1-AS:9 | chr11:32435801-32458769 | 1254 bp |
Locus conservation
| Locus conservation? |  |
 |
 |
 |
|---|---|---|---|---|
| WT1-AS | no | no | no | no |
Available literature
- Du (2016), Decreased expression of long non-coding RNA WT1-AS promotes cell proliferation and invasion in gastric cancer., Biochim. Biophys. Acta
- He (2015), LongTarget: a tool to predict lncRNA DNA-binding motifs and binding sites via Hoogsteen base-pairing analysis., Bioinformatics
- Jiang (2015), Long non-coding RNA profiling links subgroup classification of endometrioid endometrial carcinomas with trithorax and polycomb complex aberrations., Oncotarget
- Lv (2015), WT1-AS promotes cell apoptosis in hepatocellular carcinoma through down-regulating of WT1., J. Exp. Clin. Cancer Res.
- Garzon (2014), Expression and prognostic impact of lncRNAs in acute myeloid leukemia., Proc. Natl. Acad. Sci. U.S.A.
- Garding (2013), Epigenetic upregulation of lncRNAs at 13q14.3 in leukemia is linked to the In Cis downregulation of a gene cluster that targets NF-kB., PLoS Genet.
- Dallosso (2007), Alternately spliced WT1 antisense transcripts interact with WT1 sense RNA and show epigenetic and splicing defects in cancer., RNA
- Hancock (2007), A CTCF-binding silencer regulates the imprinted genes AWT1 and WT1-AS and exhibits sequential epigenetic defects during Wilms' tumourigenesis., Hum. Mol. Genet.
- Dallosso (2004), Genomic imprinting at the WT1 gene involves a novel coding transcript (AWT1) that shows deregulation in Wilms' tumours., Hum. Mol. Genet.
- Malik (2000), Identification of differential methylation of the WT1 antisense regulatory region and relaxation of imprinting in Wilms' tumor., Cancer Res.
- Malik (1995), Identification of an antisense WT1 promoter in intron 1: implications for WT1 gene regulation., Oncogene
- Campbell (1994), Antisense transcripts and protein binding motifs within the Wilms tumour (WT1) locus., Oncogene
- Eccles (1994), Cloning of novel Wilms tumor gene (WT1) cDNAs; evidence for antisense transcription of WT1., Oncogene
- Gessler (1993), Sequence of the WT1 upstream region including the Wit-1 gene., Genomics
- Huang (1990), Tissue, developmental, and tumor-specific expression of divergent transcripts in Wilms tumor., Science