Transcript: FTX:10

Basic information

LNCipedia transcript ID: FTX:10 
HGNC Gene Symbol: FTX    
HGNC Full Gene Name: FTX transcript, XIST regulator
Ensembl Gene ID: ENSG00000230590
Ensembl Transcript ID: ENST00000602576
Location (hg38): chrX:74274342-74292595
Strand: -
Class: intergenic
Sequence Ontology term: lincRNA
Transcript size: 574 bp
Exons: 5
Sources: NONCODE v4; Ensembl release 75 - Feb 2014; Ensembl release 83 - Dec 2015; Ensembl release 87 - Dec 2016; Ensembl release 90 - Aug 2017; Ensembl release 92 - Apr 2018
Alternative transcript names: NONHSAT137625; ENST00000602576.1; ENST00000602576.5
Alternative gene names: ENSG00000230590.3; FTX; ENSG00000230590.7; LINC00182; FLJ33139; ENSG00000230590.9


RNA sequence:

Structure:

Protein coding potential

Metric Raw result Interpretation
PRIDE reprocessing 2.0 0 non-coding 
Lee translation initiation sites 0 non-coding 
PhyloCSF score -89.7912 non-coding 
CPAT coding probability 0.44% non-coding 
Bazzini small ORFs 0 non-coding 

In stringent set: yes

Locus conservation

Locus conservation?
FTX:10 no no no no

Available literature

  1. Caudron-Herger (2015), Dissecting the nascent human transcriptome by analysing the RNA content of transcription factories., Nucleic Acids Res.
  2. Guo (2015), Biological significance of long non-coding RNA FTX expression in human colorectal cancer., Int J Clin Exp Med
  3. Reiche (2014), Long non-coding RNAs differentially expressed between normal versus primary breast tumor tissues disclose converse changes to breast cancer-related protein-coding genes., PLoS ONE
  4. Soma (2014), Ftx is dispensable for imprinted X-chromosome inactivation in preimplantation mouse embryos., Sci Rep
  5. Yoon (2014), PAR-CLIP analysis uncovers AUF1 impact on target RNA fate and genome integrity., Nat Commun
  6. Zhao (2014), The miR-545/374a cluster encoded in the Ftx lncRNA is overexpressed in HBV-related hepatocellular carcinoma and promotes tumorigenesis and tumor progression., PLoS ONE
  7. Chureau (2011), Ftx is a non-coding RNA which affects Xist expression and chromatin structure within the X-inactivation center region., Hum. Mol. Genet.
  8. Payer (2011), X-inactivation and X-reactivation: epigenetic hallmarks of mammalian reproduction and pluripotent stem cells., Hum. Genet.
  9. Kolesnikov (2010), [Comparative organization and the origin of noncoding regulatory RNA genes from X-chromosome inactivation center of human and mouse]., Genetika
  10. Chureau (2002), Comparative sequence analysis of the X-inactivation center region in mouse, human, and bovine., Genome Res.


LNCipedia transcript ID history

LNCipedia version LNCipedia transcript ID
3.1 lnc-RLIM-2:13
4.0 FTX:10
4.1 FTX:10
5.0 FTX:10
5.1 FTX:10
5.2 FTX:10