Transcript: GAPLINC:10

Basic information

LNCipedia transcript ID: GAPLINC:10 
HGNC Gene Symbol: GAPLINC    
HGNC Full Gene Name: gastric adenocarcinoma associated, positive CD44 regulator, long intergenic non-coding RNA
Ensembl Gene ID: ENSG00000266835
Ensembl Transcript ID: ENST00000578664
Location (hg38): chr18:3467241-3478976
Strand: +
Class: intergenic
Sequence Ontology term: lincRNA
Transcript size: 440 bp
Exons: 3
Sources: Gencode v13; Ensembl release 68 - Jul 2012; NONCODE v4; Ensembl release 75 - Feb 2014; Ensembl release 83 - Dec 2015; Ensembl release 87 - Dec 2016; Ensembl release 90 - Aug 2017; Ensembl release 92 - Apr 2018
Alternative transcript names: ENST00000578664.1; RP11-838N2.4-004; OTTHUMT00000441763.1; NONHSAT056997
Alternative gene names: ENSG00000266835.1; RP11-838N2.4; OTTHUMG00000178331.2; ENSG00000266835.5; GAPLINC; TCONS_00026238


RNA sequence:

Structure:

Protein coding potential

Metric Raw result Interpretation
PRIDE reprocessing 2.0 0 non-coding 
Lee translation initiation sites 0 non-coding 
PhyloCSF score -93.7206 non-coding 
CPAT coding probability 10.59% non-coding 
Bazzini small ORFs 0 non-coding 

In stringent set: yes

Locus conservation

Locus conservation?
GAPLINC:10 no no no no

Available literature

  1. Liu (2016), Hypoxia Promotes Gastric Cancer Malignancy Partly through the HIF-1α Dependent Transcriptional Activation of the Long Non-coding RNA GAPLINC., Front Physiol
  2. Wu (2016), Long Non-Coding RNA ucoo2kmd.1 Regulates CD44-Dependent Cell Growth by Competing for miR-211-3p in Colorectal Cancer., PLoS ONE
  3. Huang (2015), Long non-coding RNA TUG1 is up-regulated in hepatocellular carcinoma and promotes cell growth and apoptosis by epigenetically silencing of KLF2., Mol. Cancer
  4. Xie (2015), Decreased long noncoding RNA SPRY4-IT1 contributing to gastric cancer cell metastasis partly via affecting epithelial-mesenchymal transition., J Transl Med
  5. Xie (2015), Long noncoding RNA HOXA-AS2 promotes gastric cancer proliferation by epigenetically silencing P21/PLK3/DDIT3 expression., Oncotarget
  6. Hu (2014), Long noncoding RNA GAPLINC regulates CD44-dependent cell invasiveness and associates with poor prognosis of gastric cancer., Cancer Res.


LNCipedia transcript ID history

LNCipedia version LNCipedia transcript ID
3.1 lnc-TGIF1-1:7
4.0 GAPLINC:10
4.1 GAPLINC:10
5.0 GAPLINC:10
5.1 GAPLINC:10
5.2 GAPLINC:10