Gene: HOTAIR

Basic information

HGNC Gene Symbol: HOTAIR  ?
HGNC Full Gene Name: HOX transcript antisense RNA
Location (hg19): chr12:54356092-54368740
Strand: -
Transcripts: 11

Transcripts

Transcript IDLocation (hg19)Length
HOTAIR:1 chr12:54356092-54368740 2421 bp
HOTAIR:10 chr12:54357586-54360414 572 bp
HOTAIR:11 chr12:54356410-54359977 685 bp
HOTAIR:2 chr12:54356092-54368740 2368 bp
HOTAIR:3 chr12:54357533-54368731 918 bp
HOTAIR:4 chr12:54357869-54362698 560 bp
HOTAIR:5 chr12:54356092-54362698 2337 bp
HOTAIR:6 chr12:54356410-54362547 1844 bp
HOTAIR:7 chr12:54356092-54362540 2362 bp
HOTAIR:8 chr12:54356098-54362028 2207 bp
HOTAIR:9 chr12:54357685-54361139 562 bp

Locus conservation

Locus conservation?
HOTAIR yes yes

Available literature

  1. Chang (2016), Decreased expression of long non-coding RNA GAS5 indicates a poor prognosis and promotes cell proliferation and invasion in hepatocellular carcinoma by regulating vimentin., Molecular medicine reports
  2. Fayda (2016), Do circulating long non-coding RNAs (lncRNAs) (LincRNA-p21, GAS 5, HOTAIR) predict the treatment response in patients with head and neck cancer treated with chemoradiotherapy?, Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
  3. Fu (2016), Long noncoding RNA Hotair mediated angiogenesis in nasopharyngeal carcinoma by direct and indirect signaling pathways., Oncotarget
  4. Gao (2016), ROR functions as a ceRNA to regulate Nanog expression by sponging miR-145 and predicts poor prognosis in pancreatic cancer., Oncotarget
  5. Jiang (2016), The long non-coding RNA HOTAIR affects the radiosensitivity of pancreatic ductal adenocarcinoma by regulating the expression of Wnt inhibitory factor 1., Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
  6. Lennox (2016), Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides., Nucleic acids research
  7. Liu (2016), The long noncoding RNA Gm15055 represses Hoxa gene expression by recruiting PRC2 to the gene cluster., Nucleic acids research
  8. Pan (2016), A functional lncRNA HOTAIR genetic variant contributes to gastric cancer susceptibility., Molecular carcinogenesis
  9. Thorenoor (2016), Long non-coding RNA ZFAS1 interacts with CDK1 and is involved in p53-dependent cell cycle control and apoptosis in colorectal cancer., Oncotarget
  10. Xie (2016), Long non-coding RNAs in colorectal cancer., Oncotarget
  11. Abba (2015), A Molecular Portrait of High-Grade Ductal Carcinoma In Situ., Cancer research
  12. Alaimo (2015), ncPred: ncRNA-Disease Association Prediction through Tripartite Network-Based Inference., Frontiers in bioengineering and biotechnology
  13. Bayram (2015), Effect of HOTAIR rs920778 polymorphism on breast cancer susceptibility and clinicopathologic features in a Turkish population., Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
  14. Bayram (2015), A functional HOTAIR rs920778 polymorphism does not contributes to gastric cancer in a Turkish population: a case-control study., Familial cancer
  15. Bayram (2015), A functional HOTAIR rs12826786 C>T polymorphism is associated with breast cancer susceptibility and poor clinicopathological characteristics in a Turkish population: a hospital-based case-control study., Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
  16. Bhan (2015), LncRNA HOTAIR: A master regulator of chromatin dynamics and cancer., Biochimica et biophysica acta
  17. Bhan (2015), Estradiol-Induced Transcriptional Regulation of Long Non-Coding RNA, HOTAIR., Methods in molecular biology (Clifton, N.J.)
  18. Botti (2015), LncRNA HOTAIR as prognostic circulating marker and potential therapeutic target in patients with tumor diseases., Current drug targets
  19. Cabanski (2015), Pan-cancer transcriptome analysis reveals long noncoding RNAs with conserved function., RNA biology
  20. Carter (2015), Circulating long noncoding RNA GAS5 levels are correlated to prevalence of type 2 diabetes mellitus., BBA clinical
  21. Chen (2015), Calycosin and genistein induce apoptosis by inactivation of HOTAIR/p-Akt signaling pathway in human breast cancer MCF-7 cells., Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
  22. Chen (2015), SNORD76, a box C/D snoRNA, acts as a tumor suppressor in glioblastoma., Scientific reports
  23. Chen (2015), Constructing lncRNA functional similarity network based on lncRNA-disease associations and disease semantic similarity., Scientific reports
  24. Chen (2015), Predicting lncRNA-disease associations and constructing lncRNA functional similarity network based on the information of miRNA., Scientific reports
  25. Chen (2015), Radiotherapy induced Lewis lung cancer cell apoptosis via inactivating β-catenin mediated by upregulated HOTAIR., International journal of clinical and experimental pathology
  26. Cheng (2015), The long non-coding RNA HOTTIP enhances pancreatic cancer cell proliferation, survival and migration., Oncotarget
  27. Chillón (2015), Native Purification and Analysis of Long RNAs., Methods in enzymology
  28. Choudhry (2015), Hypoxic regulation of the noncoding genome and NEAT1., Briefings in functional genomics
  29. Conigliaro (2015), CD90+ liver cancer cells modulate endothelial cell phenotype through the release of exosomes containing H19 lncRNA., Molecular cancer
  30. Dang (2015), Expression and clinical significance of long non-coding RNA HNF1A-AS1 in human gastric cancer., World journal of surgical oncology
  31. Ding (2015), Long non-coding RNA PVT1 is associated with tumor progression and predicts recurrence in hepatocellular carcinoma patients., Oncology letters
  32. Ding (2015), Long non-coding RNA Loc554202 induces apoptosis in colorectal cancer cells via the caspase cleavage cascades., Journal of experimental & clinical cancer research : CR
  33. Du (2015), The association analysis of lncRNA HOTAIR genetic variants and gastric cancer risk in a Chinese population., Oncotarget
  34. Díaz-Beyá (2015), The lincRNA HOTAIRM1, located in the HOXA genomic region, is expressed in acute myeloid leukemia, impacts prognosis in patients in the intermediate-risk cytogenetic category, and is associated with a distinctive microRNA signature., Oncotarget
  35. Fan (2015), Long non-coding RNA ROR decoys gene-specific histone methylation to promote tumorigenesis., Genome biology
  36. Fan (2015), Erratum to: Long non-coding RNA ROR decoys gene-specific histone methylation to promote tumorigenesis., Genome biology
  37. Fang (2015), Probing Xist RNA Structure in Cells Using Targeted Structure-Seq., PLoS genetics
  38. Fang (2015), Long noncoding RNA-HOTAIR affects chemoresistance by regulating HOXA1 methylation in small cell lung cancer cells., Laboratory investigation; a journal of technical methods and pathology
  39. Fiscon (2015), MONSTER v1.1: a tool to extract and search for RNA non-branching structures., BMC genomics
  40. Fu (2015), Hotair mediates hepatocarcinogenesis through suppressing miRNA-218 expression and activating P14 and P16 signaling., Journal of hepatology
  41. Gaiti (2015), Dynamic and Widespread lncRNA Expression in a Sponge and the Origin of Animal Complexity., Molecular biology and evolution
  42. Gan (2015), Focusing on long noncoding RNA dysregulation in gastric cancer., Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
  43. Gandhy (2015), Specificity protein (Sp) transcription factors and metformin regulate expression of the long non-coding RNA HULC., Oncotarget
  44. Ge (2015), fMiRNA-192 and miRNA-204 Directly Suppress lncRNA HOTTIP and Interrupt GLS1-Mediated Glutaminolysis in Hepatocellular Carcinoma., PLoS genetics
  45. Guallar (2015), RNA-binding proteins in pluripotency, differentiation, and reprogramming., Frontiers in biology
  46. Guerrieri (2015), Long non-coding RNAs era in liver cancer., World journal of hepatology
  47. Guo (2015), Associations between polymorphisms of HOTAIR and risk of gastric cardia adenocarcinoma in a population of north China., Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
  48. Guo (2015), Competing endogenous RNA networks and gastric cancer., World journal of gastroenterology
  49. Guo (2015), Comprehensive analysis of lncRNA-mRNA co-expression patterns identifies immune-associated lncRNA biomarkers in ovarian cancer malignant progression., Scientific reports
  50. Gökmen-Polar (2015), Prognostic impact of HOTAIR expression is restricted to ER-negative breast cancers., Scientific reports
  51. Hajjari (2015), HOTAIR: an oncogenic long non-coding RNA in different cancers., Cancer biology & medicine
  52. Hao (2015), Prediction of long noncoding RNA functions with co-expression network in esophageal squamous cell carcinoma., BMC cancer
  53. Hao (2015), HOTAIR is upregulated in acute myeloid leukemia and that indicates a poor prognosis., International journal of clinical and experimental pathology
  54. Heubach (2015), The long noncoding RNA HOTAIR has tissue and cell type-dependent effects on HOX gene expression and phenotype of urothelial cancer cells., Molecular cancer
  55. Hu (2015), A common set of distinct features that characterize noncoding RNAs across multiple species., Nucleic acids research
  56. Hu (2015), Up-regulation of long noncoding RNA MALAT1 contributes to proliferation and metastasis in esophageal squamous cell carcinoma., Journal of experimental & clinical cancer research : CR
  57. Hu (2015), Downregulation of NUF2 inhibits tumor growth and induces apoptosis by regulating lncRNA AF339813., International journal of clinical and experimental pathology
  58. Hu (2015), NBAT1 suppresses breast cancer metastasis by regulating DKK1 via PRC2., Oncotarget
  59. Hua (2015), High expression of long non-coding RNA ANRIL is associated with poor prognosis in hepatocellular carcinoma., International journal of clinical and experimental pathology
  60. Huang (2015), HBx-related long non-coding RNA DBH-AS1 promotes cell proliferation and survival by activating MAPK signaling in hepatocellular carcinoma., Oncotarget
  61. Imam (2015), The lncRNA NRON modulates HIV-1 replication in a NFAT-dependent manner and is differentially regulated by early and late viral proteins., Scientific reports
  62. Iyer (2015), The landscape of long noncoding RNAs in the human transcriptome., Nature genetics
  63. Jiang (2015), LncRNA2Function: a comprehensive resource for functional investigation of human lncRNAs based on RNA-seq data., BMC genomics
  64. Jiang (2015), Long non-coding RNA profiling links subgroup classification of endometrioid endometrial carcinomas with trithorax and polycomb complex aberrations., Oncotarget
  65. Jiang (2015), Novel insights into a treatment for aplastic anemia based on the advanced proliferation of bone marrow‑derived mesenchymal stem cells induced by fibroblast growth factor 1., Molecular medicine reports
  66. Jing (2015), HOTAIR enhanced aggressive biological behaviors and induced radio-resistance via inhibiting p21 in cervical cancer., Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
  67. Ke (2015), Knockdown of long non-coding RNA HOTAIR inhibits malignant biological behaviors of human glioma cells via modulation of miR-326., Oncotarget
  68. Kim (2015), Genome-wide transcript profiling reveals novel breast cancer-associated intronic sense RNAs., PloS one
  69. Kong (2015), Targeting HOTAIR Induces Mitochondria Related Apoptosis and Inhibits Tumor Growth in Head and Neck Squamous Cell Carcinoma in vitro and in vivo., Current molecular medicine
  70. Koufariotis (2015), A catalogue of novel bovine long noncoding RNA across 18 tissues., PloS one
  71. Li (2015), Expression of the long non-coding RNAs MEG3, HOTAIR, and MALAT-1 in non-functioning pituitary adenomas and their relationship to tumor behavior., Pituitary
  72. Li (2015), Nuclear factor of activated T cells 5 maintained by Hotair suppression of miR-568 upregulates S100 calcium binding protein A4 to promote breast cancer metastasis., Breast cancer research : BCR
  73. Li (2015), A high level of circulating HOTAIR is associated with progression and poor prognosis of cervical cancer., Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
  74. Li (2015), MDR1 will play a key role in pharmacokinetic changes under hypoxia at high altitude and its potential regulatory networks., Drug metabolism reviews
  75. Li (2015), Infiltrating mast cells enhance prostate cancer invasion via altering LncRNA-HOTAIR/PRC2-androgen receptor (AR)-MMP9 signals and increased stem/progenitor cell population., Oncotarget
  76. Li (2015), Expression of long non-coding RNA DLX6-AS1 in lung adenocarcinoma., Cancer cell international
  77. Li (2015), Study on expression of lncRNA RGMB-AS1 and repulsive guidance molecule b in non-small cell lung cancer., Diagnostic pathology
  78. Li (2015), Prognostic role of HOTAIR in four estrogen-dependent malignant tumors: a meta-analysis., OncoTargets and therapy
  79. Li (2015), LncRNA HOTAIR promotes human liver cancer stem cell malignant growth through downregulation of SETD2., Oncotarget
  80. Li (2015), Overexpression of long non-coding RNA HOTAIR leads to chemoresistance by activating the Wnt/β-catenin pathway in human ovarian cancer., Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
  81. Li (2015), LncRNA ontology: inferring lncRNA functions based on chromatin states and expression patterns., Oncotarget
  82. Li (2015), Erratum to: Overexpression of long non-coding RNA HOTAIR leads to chemoresistance by activating the Wnt/β-catenin pathway in human ovarian cancer., Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
  83. Liu (2015), Carboplatin-docetaxel-induced activity against ovarian cancer is dependent on up-regulated lncRNA PVT1., International journal of clinical and experimental pathology
  84. Liu (2015), Epigenetic silencing of p21 by long non-coding RNA HOTAIR is involved in the cell cycle disorder induced by cigarette smoke extract., Toxicology letters
  85. Liu (2015), Over-expression of lncRNA DANCR is associated with advanced tumor progression and poor prognosis in patients with colorectal cancer., International journal of clinical and experimental pathology
  86. Loewen (2015), Functions of lncRNA HOTAIR in lung cancer., Journal of hematology & oncology
  87. Martínez-Fernández (2015), Analysis of the Polycomb-related lncRNAs HOTAIR and ANRIL in bladder cancer., Clinical epigenetics
  88. Martínez-Fernández (2015), EZH2 in Bladder Cancer, a Promising Therapeutic Target., International journal of molecular sciences
  89. Mohankumar (2015), Extracellular vesicle long noncoding RNA as potential biomarkers of liver cancer., Briefings in functional genomics
  90. Na (2015), Long non-coding RNA UCA1 contributes to the progression of prostate cancer and regulates proliferation through KLF4-KRT6/13 signaling pathway., International journal of clinical and experimental medicine
  91. Nie (2015), Long noncoding RNA ANRIL promotes non-small cell lung cancer cell proliferation and inhibits apoptosis by silencing KLF2 and P21 expression., Molecular cancer therapeutics
  92. Nwigwe (2015), Boundary Associated Long Noncoding RNA Mediates Long-Range Chromosomal Interactions., PloS one
  93. Oliver (2015), Disruption of Visc-2, a Brain-Expressed Conserved Long Noncoding RNA, Does Not Elicit an Overt Anatomical or Behavioral Phenotype., Cerebral cortex (New York, N.Y. : 1991)
  94. Pastori (2015), The Bromodomain protein BRD4 controls HOTAIR, a long noncoding RNA essential for glioblastoma proliferation., Proceedings of the National Academy of Sciences of the United States of America
  95. Pedram Fatemi (2015), Screening for Small-Molecule Modulators of Long Noncoding RNA-Protein Interactions Using AlphaScreen., Journal of biomolecular screening
  96. Pei (2015), Notch-1 promotes breast cancer cells proliferation by regulating LncRNA GAS5., International journal of clinical and experimental medicine
  97. Peng (2015), Long non-coding RNA MEG3 functions as a competing endogenous RNA to regulate gastric cancer progression., Journal of experimental & clinical cancer research : CR
  98. Peschansky (2015), Changes in expression of the long non-coding RNA FMR4 associate with altered gene expression during differentiation of human neural precursor cells., Frontiers in genetics
  99. Pircher (2015), Ribosome-associated ncRNAs: an emerging class of translation regulators., RNA biology
  100. Qiu (2015), The long non-coding RNA HOTAIR promotes the proliferation of serous ovarian cancer cells through the regulation of cell cycle arrest and apoptosis., Experimental cell research
  101. Qiu (2015), A novel lncRNA, LUADT1, promotes lung adenocarcinoma proliferation via the epigenetic suppression of p27., Cell death & disease
  102. Quek (2015), lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs., Nucleic acids research
  103. Ragusa (2015), Non-coding landscapes of colorectal cancer., World journal of gastroenterology
  104. Richards (2015), A functional variant in HOXA11-AS, a novel long non-coding RNA, inhibits the oncogenic phenotype of epithelial ovarian cancer., Oncotarget
  105. Rupaimoole (2015), Long Noncoding RNA Ceruloplasmin Promotes Cancer Growth by Altering Glycolysis., Cell reports
  106. Scarola (2015), Epigenetic silencing of Oct4 by a complex containing SUV39H1 and Oct4 pseudogene lncRNA., Nature communications
  107. Sharma (2015), Bridging Links between Long Noncoding RNA HOTAIR and HPV Oncoprotein E7 in Cervical Cancer Pathogenesis., Scientific reports
  108. Shen (2015), Exploration of Deregulated Long Non-Coding RNAs in Association with Hepatocarcinogenesis and Survival., Cancers
  109. Shi (2015), Up-regulation of long non-coding RNA Sox2ot promotes hepatocellular carcinoma cell metastasis and correlates with poor prognosis., International journal of clinical and experimental pathology
  110. Shi (2015), Microvascular invasion in hepatocellular carcinoma overexpression promotes cell proliferation and inhibits cell apoptosis of hepatocellular carcinoma via inhibiting miR-199a expression., OncoTargets and therapy
  111. Silva (2015), The Clinical Relevance of Long Non-Coding RNAs in Cancer., Cancers
  112. Smolle (2015), Long Non-Coding RNAs in Endometrial Carcinoma., International journal of molecular sciences
  113. Somarowthu (2015), HOTAIR forms an intricate and modular secondary structure., Molecular cell
  114. Song (2015), Long non-coding RNA HOTAIR promotes HLA-G expression via inhibiting miR-152 in gastric cancer cells., Biochemical and biophysical research communications
  115. Sugihara (2015), Noncoding RNA Expression Aberration Is Associated with Cancer Progression and Is a Potential Biomarker in Esophageal Squamous Cell Carcinoma., International journal of molecular sciences
  116. Sun (2015), Increased expression of lncRNA HULC indicates a poor prognosis and promotes cell metastasis in osteosarcoma., International journal of clinical and experimental pathology
  117. Sun (2015), Involvement of lncRNA dysregulation in gastric cancer., Histology and histopathology
  118. Sun (2015), Long non-coding RNA HOTAIR regulates cyclin J via inhibition of microRNA-205 expression in bladder cancer., Cell death & disease
  119. Sun (2015), A potential prognostic long non-coding RNA signature to predict metastasis-free survival of breast cancer patients., Scientific reports
  120. Tan (2015), Reprogramming during epithelial to mesenchymal transition under the control of TGFβ., Cell adhesion & migration
  121. Tan (2015), HOTAIR inhibited intracellular Ca2+ via regulation of Cav1.2 channel in human cardiomyocytes., Cellular and molecular biology (Noisy-le-Grand, France)
  122. Tantai (2015), Combined identification of long non-coding RNA XIST and HIF1A-AS1 in serum as an effective screening for non-small cell lung cancer., International journal of clinical and experimental pathology
  123. Teschendorff (2015), HOTAIR and its surrogate DNA methylation signature indicate carboplatin resistance in ovarian cancer., Genome medicine
  124. Tong (2015), Identification of the long non-coding RNA POU3F3 in plasma as a novel biomarker for diagnosis of esophageal squamous cell carcinoma., Molecular cancer
  125. Wan (2015), Aberrantly expressed long noncoding RNAs in human intervertebral disc degeneration: a microarray related study., Arthritis research & therapy
  126. Wang (2015), Overexpression of Long Non-Coding RNA HOTAIR Promotes Tumor Growth and Metastasis in Human Osteosarcoma., Molecules and cells
  127. Wang (2015), Prognostic value of long noncoding RNA HOTAIR in digestive system malignancies., Journal of gastroenterology and hepatology
  128. Wang (2015), Downregulated lincRNA HOTAIR expression in ovarian cancer stem cells decreases its tumorgeniesis and metastasis by inhibiting epithelial-mesenchymal transition., Cancer cell international
  129. Wang (2015), Combined inhibition of EGFR and c-ABL suppresses the growth of triple-negative breast cancer growth through inhibition of HOTAIR., Oncotarget
  130. Wang (2015), Long noncoding RNA derived from CD244 signaling epigenetically controls CD8+ T-cell immune responses in tuberculosis infection., Proceedings of the National Academy of Sciences of the United States of America
  131. Wang (2015), Genome-scale long noncoding RNA expression pattern in squamous cell lung cancer., Scientific reports
  132. Wang (2015), LncRNA NALT interaction with NOTCH1 promoted cell proliferation in pediatric T cell acute lymphoblastic leukemia., Scientific reports
  133. Wang (2015), Upregulated lncRNA-UCA1 contributes to progression of lung cancer and is closely related to clinical diagnosis as a predictive biomarker in plasma., International journal of clinical and experimental medicine
  134. Wang (2015), LncRNA MALAT1 enhances oncogenic activities of EZH2 in castration-resistant prostate cancer., Oncotarget
  135. Wang (2015), The ratio of FoxA1 to FoxA2 in lung adenocarcinoma is regulated by LncRNA HOTAIR and chromatin remodeling factor LSH., Scientific reports
  136. Wang (2015), Serum LncRNAs Profiles Serve as Novel Potential Biomarkers for the Diagnosis of HBV-Positive Hepatocellular Carcinoma., PloS one
  137. Wei (2015), Transcriptome profiling of esophageal squamous cell carcinoma reveals a long noncoding RNA acting as a tumor suppressor., Oncotarget
  138. Werner (2015), Nuclear Fractionation Reveals Thousands of Chromatin-Tethered Noncoding RNAs Adjacent to Active Genes., Cell reports
  139. Wongtrakoongate (2015), Association of the Long Non-coding RNA Steroid Receptor RNA Activator (SRA) with TrxG and PRC2 Complexes., PLoS genetics
  140. Wu (2015), The long non-coding RNA HNF1A-AS1 regulates proliferation and metastasis in lung adenocarcinoma., Oncotarget
  141. Wu (2015), Long non-coding RNA HOTAIR promotes tumor cell invasion and metastasis by recruiting EZH2 and repressing E-cadherin in oral squamous cell carcinoma., International journal of oncology
  142. Wu (2015), Expression of long noncoding RNA-HOX transcript antisense intergenic RNA in oral squamous cell carcinoma and effect on cell growth., Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
  143. Wu (2015), Overexpression of long non-coding RNA HOTAIR predicts a poor prognosis in patients with acute myeloid leukemia., Oncology letters
  144. Xie (2015), Long noncoding RNA HOXA-AS2 promotes gastric cancer proliferation by epigenetically silencing P21/PLK3/DDIT3 expression., Oncotarget
  145. Xing (2015), Long non-coding RNA HOTAIR modulates c-KIT expression through sponging miR-193a in acute myeloid leukemia., FEBS letters
  146. Xue (2015), Genetic variants in lncRNA HOTAIR are associated with risk of colorectal cancer., Mutagenesis
  147. Xue (2015), Decreased expression of long non-coding RNA NBAT-1 is associated with poor prognosis in patients with clear cell renal cell carcinoma., International journal of clinical and experimental pathology
  148. Xue (2015), LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer., Oncogene
  149. Yamamoto (2015), Breast Cancer: Radiogenomic Biomarker Reveals Associations among Dynamic Contrast-enhanced MR Imaging, Long Noncoding RNA, and Metastasis., Radiology
  150. Yan (2015), Prognostic significance of long non-coding RNA PCAT-1 expression in human hepatocellular carcinoma., International journal of clinical and experimental pathology
  151. Yan (2015), Polymorphisms in lncRNA HOTAIR and susceptibility to breast cancer in a Chinese population., Cancer epidemiology
  152. Yang (2015), Overexpression of Long Non-Coding RNA ZXF2 Promotes Lung Adenocarcinoma Progression Through c-Myc Pathway., Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
  153. Yang (2015), Expression profile of long non-coding RNAs is altered in endometrial cancer., International journal of clinical and experimental medicine
  154. Yang (2015), High MALAT1 expression predicts a poor prognosis of cervical cancer and promotes cancer cell growth and invasion., European review for medical and pharmacological sciences
  155. Yang (2015), Knockdown of long non-coding RNA HOTAIR inhibits proliferation and invasiveness and improves radiosensitivity in colorectal cancer., Oncology reports
  156. Ye (2015), Evaluation of four genetic variants in han chinese subjects with high myopia., Journal of ophthalmology
  157. Ye (2015), Enhancing HOTAIR/MiR-10b Drives Normal Liver Stem Cells Toward a Tendency to Malignant Transformation Through Inducing Epithelial- to-Mesenchymal Transition., Rejuvenation research
  158. Ye (2015), Expression of lncRNA-CCAT1, E-cadherin and N-cadherin in colorectal cancer and its clinical significance., International journal of clinical and experimental medicine
  159. Yin (2015), SnoVectors for nuclear expression of RNA., Nucleic acids research
  160. Yin (2015), Expression Quantitative Trait Loci for CARD8 Contributes to Risk of Two Infection-Related Cancers--Hepatocellular Carcinoma and Cervical Cancer., PloS one
  161. Yu (2015), Long noncoding RNAs in hepatitis B virus-related hepatocellular carcinoma., World journal of gastroenterology
  162. Yu (2015), Long non-coding RNA HOTAIR: A novel oncogene (Review)., Molecular medicine reports
  163. Yu (2015), Long non-coding RNA growth arrest-specific transcript 5 in tumor biology., Oncology letters
  164. Zhai (2015), Long noncoding RNA MALAT1 as a putative biomarker of lymph node metastasis: a meta-analysis., International journal of clinical and experimental medicine
  165. Zhang (2015), Long non-coding RNA HOTAIR promotes glioblastoma cell cycle progression in an EZH2 dependent manner., Oncotarget
  166. Zhang (2015), HOTAIR Long Noncoding RNA Promotes Gastric Cancer Metastasis through Suppression of Poly r(C)-Binding Protein (PCBP) 1., Molecular cancer therapeutics
  167. Zhang (2015), PLK1 and HOTAIR Accelerate Proteasomal Degradation of SUZ12 and ZNF198 during Hepatitis B Virus-Induced Liver Carcinogenesis., Cancer research
  168. Zhang (2015), Circulating DNA of HOTAIR in serum is a novel biomarker for breast cancer., Breast cancer research and treatment
  169. Zhang (2015), LncRNA MALAT1 overexpression is an unfavorable prognostic factor in human cancer: evidence from a meta-analysis., International journal of clinical and experimental medicine
  170. Zhang (2015), Long non-coding RNA chromogenic in situ hybridisation signal pattern correlation with breast tumour pathology., Journal of clinical pathology
  171. Zhang (2015), LncRNA HOTAIR Enhances the Androgen-Receptor-Mediated Transcriptional Program and Drives Castration-Resistant Prostate Cancer., Cell reports
  172. Zhang (2015), Long Noncoding RNA Expression Signatures of Metastatic Nasopharyngeal Carcinoma and Their Prognostic Value., BioMed research international
  173. Zhang (2015), Overexpression of long non-coding RNA CCAT1 is a novel biomarker of poor prognosis in patients with breast cancer., International journal of clinical and experimental pathology
  174. Zhang (2015), Molecular mechanism of HEIH and HULC in the proliferation and invasion of hepatoma cells., International journal of clinical and experimental medicine
  175. Zhao (2015), Long non-coding RNA Linc00152 is involved in cell cycle arrest, apoptosis, epithelial to mesenchymal transition, cell migration and invasion in gastric cancer., Cell cycle (Georgetown, Tex.)
  176. Zhao (2015), HOTAIR is a predictive and prognostic biomarker for patients with advanced gastric adenocarcinoma receiving fluorouracil and platinum combination chemotherapy., American journal of translational research
  177. Zheng (2015), Quantitative Proteomics Analysis Reveals Novel Insights into Mechanisms of Action of Long Noncoding RNA Hox Transcript Antisense Intergenic RNA (HOTAIR) in HeLa Cells., Molecular & cellular proteomics : MCP
  178. Zhou (2015), Long noncoding RNA HOTAIR, a hypoxia-inducible factor-1α activated driver of malignancy, enhances hypoxic cancer cell proliferation, migration, and invasion in non-small cell lung cancer., Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
  179. Zhou (2015), Identification of the long non-coding RNA H19 in plasma as a novel biomarker for diagnosis of gastric cancer., Scientific reports
  180. Zhou (2015), Long Non Coding RNA MALAT1 Promotes Tumor Growth and Metastasis by inducing Epithelial-Mesenchymal Transition in Oral Squamous Cell Carcinoma., Scientific reports
  181. Zhu (2015), [Effects of long non-coding RNA-HOTAIR on the cell cycle and invasiveness of prostate cancer]., Zhonghua nan ke xue = National journal of andrology
  182. Zhu (2015), Ectopic expressed long non-coding RNA H19 contributes to malignant cell behavior of ovarian cancer., International journal of clinical and experimental pathology
  183. Zhuang (2015), Elevated expression of long intergenic non-coding RNA HOTAIR in a basal-like variant of MCF-7 breast cancer cells., Molecular carcinogenesis
  184. Zou (2015), [Long noncoding RNA HOTAIR modulates the function of trophoblast cells in pre-eclampsia]., Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
  185. Almlöf (2014), Single nucleotide polymorphisms with cis-regulatory effects on long non-coding transcripts in human primary monocytes., PloS one
  186. Barnhill (2014), High expression of CAI2, a 9p21-embedded long noncoding RNA, contributes to advanced-stage neuroblastoma., Cancer research
  187. Basu (2014), Using amino-labeled nucleotide probes for simultaneous single molecule RNA-DNA FISH., PloS one
  188. Batagov (2014), Role of genomic architecture in the expression dynamics of long noncoding RNAs during differentiation of human neuroblastoma cells., BMC systems biology
  189. Beato (2014), A new role for an old player: steroid receptor RNA Activator (SRA) represses hormone inducible genes., Transcription
  190. Bhan (2014), Bisphenol-A and diethylstilbestrol exposure induces the expression of breast cancer associated long noncoding RNA HOTAIR in vitro and in vivo., The Journal of steroid biochemistry and molecular biology
  191. Brunner (2014), Transcriptional profiling of long non-coding RNAs and novel transcribed regions across a diverse panel of archived human cancers., Genome biology
  192. Brunner (2014), A shared transcriptional program in early breast neoplasias despite genetic and clinical distinctions., Genome biology
  193. Cai (2014), Long noncoding RNA HOTAIR can serve as a common molecular marker for lymph node metastasis: a meta-analysis., Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
  194. Cai (2014), HOTAIR: a cancer-related long non-coding RNA., Neoplasma
  195. Cao (2014), [Genome wide screening and characterization of long non-coding RNAs in esophageal cancer]., Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics
  196. Carrion (2014), The long non-coding HOTAIR is modulated by cyclic stretch and WNT/β-CATENIN in human aortic valve cells and is a novel repressor of calcification genes., PloS one
  197. Chakravadhanula (2014), Expression of the HOX genes and HOTAIR in atypical teratoid rhabdoid tumors and other pediatric brain tumors., Cancer genetics
  198. Chen (2014), Cisplatin and paclitaxel target significant long noncoding RNAs in laryngeal squamous cell carcinoma., Medical oncology (Northwood, London, England)
  199. Chi (2014), Role of BC040587 as a predictor of poor outcome in breast cancer., Cancer cell international
  200. Chiyomaru (2014), Long non-coding RNA HOTAIR is targeted and regulated by miR-141 in human cancer cells., The Journal of biological chemistry
  201. Cifuentes-Rojas (2014), Regulatory interactions between RNA and polycomb repressive complex 2., Molecular cell
  202. Cogill (2014), Co-expression Network Analysis of Human lncRNAs and Cancer Genes., Cancer informatics
  203. Collier (2014), Regulation of the Th1 genomic locus from Ifng through Tmevpg1 by T-bet., Journal of immunology (Baltimore, Md. : 1950)
  204. Davidovich (2014), A dimeric state for PRC2., Nucleic acids research
  205. Deng (2014), Up-regulation of 91H promotes tumor metastasis and predicts poor prognosis for patients with colorectal cancer., PloS one
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